Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.61 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | CCR8 | P51685 | 2/20 | 0.61 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CBFB | Q13951 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575918 | 0.83 | CCR1 (0.41) | CCR1CCR5CCR8POLBNPC1 | |
| SCHEMBL182529 | 0.78 | CCR1 (1.00) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL29395249 | 0.78 | CCR1 (1.00) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL9014019 | 0.77 | CCR1 (0.80) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL9014003 | 0.77 | CCR1 (0.80) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL14554394 | 0.77 | CCR1 (0.80) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL20761804 | 0.76 | CCR1 (0.41) | CCR1CCR5CCR8POLBNPC1 | |
| Methane SCHEMBL21386924 | 0.76 | CCR1 (0.95) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL8746042 | 0.76 | CCR1 (0.95) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL9135460 | 0.76 | CCR1 (0.95) | CCR1CCR5CCR8NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409425-B2 | Biosensor coating composition and methods thereof | ABBOTT DIABETES CARE INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8409425-B2 | Biosensor coating composition and methods thereof | ABBOTT DIABETES CARE INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-20130034664-A1 | Biosensor Coating Composition and Methods Thereof | ABBOTT DIABETES CARE INC. | 2013-02-07 | — | — | US | disclosed |
| US-20130034664-A1 | Biosensor Coating Composition and Methods Thereof | ABBOTT DIABETES CARE INC. | 2013-02-07 | — | — | US | disclosed |
| US-8262874-B2 | Biosensor coating composition and methods thereof | ABBOTT DIABETES CARE INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-8262874-B2 | Biosensor coating composition and methods thereof | ABBOTT DIABETES CARE INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-8262874-B2 | Biosensor coating composition and methods thereof | ABBOTT DIABETES CARE INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-8226814-B2 | Transition metal complexes with pyridyl-imidazole ligands | ABBOTT DIABETES CARE INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-8226814-B2 | Transition metal complexes with pyridyl-imidazole ligands | ABBOTT DIABETES CARE INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-8226814-B2 | Transition metal complexes with pyridyl-imidazole ligands | ABBOTT DIABETES CARE INC. (US) | 2012-07-24 | — | — | US | disclosed |
| WO-2009129108-A1 | BIOSENSOR COATING COMPOSITIONS AND METHODS THEREOF | ABBOTT DIABETES CARE INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| US-20090255811-A1 | BIOSENSOR COATING COMPOSITION AND METHODS THEREOF | ABBOTT DIABETES CARE INC. | 2009-10-15 | — | — | US | disclosed |
| US-20090255811-A1 | BIOSENSOR COATING COMPOSITION AND METHODS THEREOF | ABBOTT DIABETES CARE INC. | 2009-10-15 | — | — | US | disclosed |
| US-20090255811-A1 | BIOSENSOR COATING COMPOSITION AND METHODS THEREOF | ABBOTT DIABETES CARE INC. | 2009-10-15 | — | — | US | disclosed |
| US-20090095642-A1 | TRANSITION METAL COMPLEXES WITH PYRIDYL-IMIDAZOLE LIGANDS | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090095642-A1 | TRANSITION METAL COMPLEXES WITH PYRIDYL-IMIDAZOLE LIGANDS | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090095642-A1 | TRANSITION METAL COMPLEXES WITH PYRIDYL-IMIDAZOLE LIGANDS | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | disclosed |