Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263051 | 1.00 | HTR2C (0.55) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL757111 | 1.00 | HTR2C (0.55) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL4253059 | 0.97 | HTR2C (0.55) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL4253061 | 0.97 | HTR2C (0.55) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL7096910 | 0.83 | HTR2C (0.66) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL7865958 | 0.83 | HTR2C (0.66) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| SCHEMBL7096911 | 0.83 | HTR2C (0.66) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| Hydrochloric Acid SCHEMBL7000161 | 0.81 | HTR2C (0.67) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| Hydrochloric Acid SCHEMBL8156348 | 0.81 | HTR2C (0.67) | HTR2CHTR2AHTR2BDPP4SLC9A1 | |
| Hydrochloric Acid SCHEMBL7000158 | 0.81 | HTR2C (0.67) | HTR2CHTR2AHTR2BDPP4SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833782-B1 | CYCLOALKYLAMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | EP | disclosed |