Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | RAD52 | P43351 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536488 | 0.82 | KDM4E (0.78) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL3537588 | 0.80 | MEN1 (1.00) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL15814003 | 0.80 | MEN1 (0.78) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL12668583 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL3542061 | 0.79 | KDM4E (0.77) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL3542063 | 0.78 | KDM4E (0.76) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL8872491 | 0.78 | MEN1 (0.74) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL20241176 | 0.77 | PTGS2 (0.71) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL2840123 | 0.77 | KDM4E (0.78) | KDM4EALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL3541028 | 0.76 | MEN1 (0.78) | KDM4EALDH1A1HPGDL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |