SCHEMBL4260946

SCHEMBL4260946

C(#Cc1ccccc1)C1=CC=CC[CH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.46
MAPT P10636 3/20 0.38
GRM5 P41594 6/20 0.35
NPC1 O15118 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 3/20 0.34
CYP1A2 P05177 3/20 0.34
CYP3A4 P08684 3/20 0.34
CYP2C9 P11712 3/20 0.34
CYP2C19 P33261 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MTOR P42345 1/20 0.34
KCNH2 Q12809 1/20 0.33
LMNA P02545 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7134455 0.69 APP (0.52) APPMAPTGRM5NPC1KDM4E
SCHEMBL7134452 0.69 APP (0.52) APPMAPTGRM5NPC1KDM4E
Diphenylacetylene SCHEMBL68254 0.68 APP (1.00) APPMAPTGRM5NPC1KDM4E
Diphenylacetylene SCHEMBL29188592 0.68 APP (1.00) APPMAPTGRM5NPC1KDM4E
Diphenylacetylene SCHEMBL960609 0.68 APP (1.00) APPMAPTGRM5NPC1KDM4E
SCHEMBL8030260 0.67
SCHEMBL1993951 0.66
SCHEMBL5169115 0.65 APP (0.46) APPMAPTGRM5NPC1KDM4E
Diphenylacetylene SCHEMBL23754282 0.65 APP (0.92) APPMAPTGRM5NPC1KDM4E
Diphenylacetylene SCHEMBL9273707 0.65 APP (0.92) APPMAPTGRM5NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 EP disclosed
WO-2001003126-A9 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV CALIFORNIA (US) 2002-08-01 WO disclosed
EP-1210714-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE The Regents of the University of California (US) 2002-06-05 EP disclosed
WO-2001003126-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-01-11 WO disclosed