Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255561 | 0.84 | MCHR1 (0.45) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| SCHEMBL4256547 | 0.81 | IRAK4 (0.41) | MCHR1IRAK4ADRA2AADRA1AHRH1 | |
| Trifluoroacetic Acid SCHEMBL4261967 | 0.77 | MCHR1 (0.62) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| SCHEMBL4263661 | 0.76 | MCHR1 (0.69) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| SCHEMBL4263667 | 0.76 | MCHR1 (0.69) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL4257335 | 0.75 | MCHR1 (0.67) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL4257343 | 0.75 | MCHR1 (0.67) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| SCHEMBL6462481 | 0.75 | KDM4E (0.50) | MCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL6456487 | 0.75 | MCHR1 (0.49) | MCHR1ADRA2AADRA1AHRH1CCNK | |
| SCHEMBL6456465 | 0.75 | MCHR1 (0.47) | MCHR1ADRA2AADRA1AHRH1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | MCHR1 3/4885KDR 1066/4885KCNQ3 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.