Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707186 | 0.85 | RAB9A (0.79) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL9265040 | 0.85 | RAB9A (0.79) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL13105707 | 0.84 | RAB9A (0.69) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL19445791 | 0.83 | RAB9A (0.72) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL24673320 | 0.83 | NPC1 (0.73) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL307051 | 0.83 | NPC1 (0.73) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL5168314 | 0.83 | NPC1 (0.73) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL23594174 | 0.83 | NPC1 (0.73) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL8396558 | 0.83 | NPC1 (0.73) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL1928387 | 0.82 | RAB9A (0.67) | RAB9ANPC1PKML3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | disclosed |