⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697406 | 1.00 | — | — | |
| SCHEMBL27482736 | 0.97 | — | — | |
| SCHEMBL28040600 | 0.97 | NOS3 (0.39) | — | |
| SCHEMBL316819 | 0.79 | KDM4E (0.38) | — | |
| SCHEMBL3762114 | 0.79 | ESR1 (0.33) | — | |
| SCHEMBL11539994 | 0.79 | KDM4E (0.38) | — | |
| SCHEMBL40655 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL9331652 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL9331061 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL9331190 | 0.78 | NOS3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207241-A1 | HALOGEN-SUBSTITUTED ISOINDOLINE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-11-02 | — | — | WO | claimed |
| US-20230242572-A1 | a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | JIANGXI NORMAL UNIVERSITY (CN) | 2023-08-03 | — | — | US | claimed |
| CN-113292430-B | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | claimed |
| EP-3988100-A1 | ADENOSINE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR STEREOISOMERIDE THEREOF, AND USE | Academy Of Military Medical Sciences (CN) | 2022-04-27 | — | — | EP | claimed |
| CN-114025763-A | Adenosine compound, pharmaceutically acceptable salt or stereoisomer thereof and application | 中国人民解放军军事科学院军事医学研究院 | 2022-02-08 | — | — | CN | claimed |
| CN-113292430-A | Alpha-carbonyl alkenyl ester compound and preparation method and application thereof | 江西师范大学 | 2021-08-24 | — | — | CN | claimed |
| US-20210246137-A1 | COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-08-12 | — | — | US | claimed |
| WO-2020253866-A1 | ADENOSINE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR STEREOISOMERIDE THEREOF, AND USE | 中国人民解放军军事科学院军事医学研究院 | 2020-12-24 | — | — | WO | claimed |
| US-20190315740-A1 | COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-10-17 | — | — | US | claimed |
| CN-110023312-A | The Compounds and methods for for preventing malarial parasite from propagating | 由卫生与公众服务部部长代表的美利坚合众国 | 2019-07-16 | — | — | CN | claimed |
| US-20030158186-A1 | Compositions and methods for treating heart failure | CYTOKINETICS, INCORPORATED | 2003-08-21 | — | — | US | claimed |
| WO-2003059265-A2 | COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE | CYTOKINETICS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | claimed |
| US-20030018059-A1 | Serine protease inhibitors | PROTHERICS MOLECULAR DESIGN LIMITED (GB) | 2003-01-23 | — | — | US | claimed |
| EP-1240154-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2002-09-18 | — | — | EP | claimed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | claimed |
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | claimed |
| US-5843933-A | 11β-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | claimed |
| US-5728689-A | ANTIGESTAGENIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | claimed |