SCHEMBL426218

SCHEMBL426218

C(#Cc1ccc2cc3ccccc3cc2c1C#Cc1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
ASIC3 Q9UHC3 2/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
CYP1A2 P05177 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1B1 Q16678 2/20 0.36
HIF1A Q16665 1/20 0.36
GRM5 P41594 1/20 0.36
GAA P10253 1/20 0.35
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30015220 1.00 APP (0.41) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL29361256 0.98 APP (0.40) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL1620142 0.98 APP (0.40) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL31425775 0.98 APP (0.40) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL5167733 0.87 PIK3CA (0.37) ALDH1A1HSD17B10KDM4ENPC1CYP1A2
SCHEMBL29365387 0.87 CYP2A6 (0.34) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL6370266 0.84 APP (0.46) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL1620112 0.83 ASIC3 (0.31) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL1155254 0.82 APP (0.44) APPASIC3ALDH1A1HSD17B10KDM4E
SCHEMBL8079828 0.81 APP (0.40) APPASIC3ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076500-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. (US) 2022-10-26 EP claimed
EP-3661974-A1 PHOTOPOLYMERISABLE COMPOSITION, MATERIAL OBTAINED BY POLYMERISING SUCH A COMPOSITION AND 3D PRINTING METHOD USING SUCH A COMPOSITION Ecole Normale Superieure De Lyon (FR) 2020-06-10 EP claimed
US-9587173-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2017-03-07 US claimed
US-20160320621-A1 HEAD-MOUNTED DISPLAY WITH FILTER FUNCTION ESSILOR INTERNATIONAL (FR) 2016-11-03 US claimed
EP-3087312-A1 HEAD-MOUNTED DISPLAY WITH FILTER FUNCTION Essilor International (Compagnie Générale d'Optique) (FR) 2016-11-02 EP claimed
US-20150368555-A1 CHEMILUMINESCENT SYSTEM GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2015-12-24 US claimed
US-9116147-B2 Compositions and methods for detection of small molecules using dyes derivatized with analyte responsive receptors in a chemiluminescent assay BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-08-25 US claimed
US-9109156-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2015-08-18 US claimed
US-20140300857-A1 OPHTHALMIC FILTER ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQU E) (FR) 2014-10-09 US claimed
US-20140166949-A1 Chemiluminescent system GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2014-06-19 US claimed
WO-2002094910-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF IN LIGHT-EMITTING DEVICES SRI INTERNATIONAL (US) 2002-11-28 WO claimed
US-6406667-B1 FLUORESCENT COMPOUNDS FOR CHEMILUMINESCENT COMPOUNDS DADE BEHRING MARBURG GMBH (DE) 2002-06-18 US claimed
US-6075106-A (Co)polymers based on vinyl units and use thereof in electroluminescent devices D-51368 BAYER AG (DE) 2000-06-13 US claimed
EP-0712426-B1 FLUORESCENT LATEX COMPRISING AT LEAST TWO FLUOROCHROMES, METHOD FOR PRODUCING SAME, AND USE THEREOF PROLABO SA (FR) 1997-06-04 EP claimed
EP-0277347-B1 DOUBLE REVERSE CHEMILUMINESCENT LIGHTING DEVICE AMERICAN CYANAMID COMPANY (US) 1991-05-02 EP claimed
EP-0251139-B1 CHEMILUMINESCENT COMPOSITION, AND A REACTIVE COMPONENT SUITABLE FOR SUCH A COMPOSITION FARMITALIA CARLO ERBA S.r.l. (IT) 1990-09-26 EP claimed
US-4375423-A Index-matched phosphor scintillator structures GENERAL ELECTRIC COMPANY (US) 1983-03-01 US claimed
US-4374749-A Index-matched phosphor scintillator structures GENERAL ELECTRIC COMPANY (US) 1983-02-22 US claimed
US-4316817-A Index-matched phosphor scintillator structures GENERAL ELECTRIC COMPANY (US) 1982-02-23 US claimed
US-4262202-A Scintillator detector array GENERAL ELECTRIC COMPANY (US) 1981-04-14 US claimed