SCHEMBL4262691

SCHEMBL4262691

CCO[Si](C)(CCCP(=O)(OCC)OCC)OCC

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.45
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5486933 0.93 PPARD (0.42) PPARDTSHR
SCHEMBL9327121 0.88 PPARD (0.48) PPARDTSHRTP53TDP1
SCHEMBL28971492 0.85 PPARD (0.45) PPARDTSHRTP53TDP1CA12
SCHEMBL3680110 0.82 PPARD (0.47) PPARDTSHRTP53TDP1CA12
SCHEMBL10882815 0.81
SCHEMBL26455309 0.80 PPARD (0.48) PPARDTSHRTP53TDP1
SCHEMBL26455501 0.79 PPARD (0.44) PPARDTSHRTP53TDP1
SCHEMBL26455197 0.79 PPARD (0.44) PPARDTSHRTP53TDP1
SCHEMBL20875719 0.78 LPAR3 (0.43) TDP1
SCHEMBL26454326 0.78 PPARD (0.47) PPARDTSHRTP53TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2963066-B1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORP (JP) 2017-12-27 EP disclosed
US-20160009903-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORPORATION (JP) 2016-01-14 US disclosed
EP-2963066-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR Corporation (JP) 2016-01-06 EP disclosed
US-8586259-B2 Proton exchange membranes based on heterocycles and acids through an organic-inorganic hybrid process GEORGIA TECH RESEARCH CORPORATION (US) 2013-11-19 US disclosed
US-20090297910-A1 Proton Exchange Membranes Based on Heterocycles and Acids Through An Organic-Inorganic Hybrid Process TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2009-12-03 US disclosed