SCHEMBL20875719

SCHEMBL20875719

CCO[Si](C)(CCCP(=O)(O)O)OCC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.43
LPAR2 Q9HBW0 1/20 0.43
TYMS P04818 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
BBOX1 O75936 2/20 0.38
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
NFKB1 P19838 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
S1PR2 O95136 6/20 0.36
S1PR1 P21453 6/20 0.36
S1PR3 Q99500 6/20 0.36
S1PR4 O95977 5/20 0.36
S1PR5 Q9H228 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18832098 0.88 LPAR3 (0.37) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL28289622 0.85 LPAR3 (0.45) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL7021919 0.82 LPAR3 (0.45) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL20875717 0.79 TYMS (0.46) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL4262691 0.78 PPARD (0.45) TDP1
SCHEMBL20875716 0.76 LPAR3 (0.48) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL7587131 0.75 LPAR3 (0.37) LPAR3LPAR2TYMSALDH1A1TDP1
SCHEMBL704022 0.75
SCHEMBL646411 0.75
SCHEMBL22370095 0.74 LPAR3 (0.52) LPAR3LPAR2TYMSALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844143-B2 Modified rubber containing silicon and phosphorus, composition and manufacturing method thereof TSRC CORPORATION (TW) 2020-11-24 US disclosed
EP-3470438-B1 MODIFIED RUBBER CONTAINING SI AND P, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC CORP (TW) 2020-05-13 EP disclosed
EP-3470438-A1 MODIFIED RUBBER CONTAINING SI AND P, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC Corporation (TW) 2019-04-17 EP disclosed
US-20190106511-A1 MODIFIED RUBBER CONTAINING SILICON AND PHOSPHORUS, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2019-04-11 US disclosed