Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 17/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263636 | 1.00 | CNR1 (0.51) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4262318 | 0.90 | MCHR1 (0.56) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4262312 | 0.90 | MCHR1 (0.56) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4271943 | 0.89 | SMYD3 (0.56) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4258106 | 0.89 | MCHR1 (0.58) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4258098 | 0.89 | MCHR1 (0.58) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4271948 | 0.89 | SMYD3 (0.56) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| Hydrochloric Acid SCHEMBL4262655 | 0.89 | SMYD3 (0.55) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| Hydrochloric Acid SCHEMBL4262660 | 0.89 | SMYD3 (0.55) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL4266211 | 0.87 | MCHR1 (0.57) | CNR1KCNH2AURKBMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | claimed |
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | CNR1 114/4885KCNH2 3317/4885AURKB 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.