SCHEMBL4264017

SCHEMBL4264017

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 8/20 0.71
▸ LMNA P02545 8/20 0.71
▸ TSHR P16473 5/20 0.71
▸ MAPT P10636 5/20 0.71
▸ NR3C1 P04150 4/20 0.71
▸ PGR P06401 4/20 0.71
▸ AR P10275 4/20 0.71
▸ NR1I2 O75469 3/20 0.71
▸ CYP2C9 P11712 3/20 0.71
▸ CYP2C19 P33261 2/20 0.71
▸ CYP17A1 P05093 2/20 0.71
▸ OPRK1 P41145 1/20 0.71
▸ CYP19A1 P11511 3/20 0.69
▸ HSD17B10 Q99714 4/20 0.61
▸ SHBG P04278 4/20 0.61
▸ SERPINA6 P08185 4/20 0.61
▸ MAPK1 P28482 4/20 0.61
▸ GPBAR1 Q8TDU6 3/20 0.61
▸ SIGMAR1 Q99720 3/20 0.61
▸ SNCA P37840 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4264019 1.00 CYP3A4 (0.71) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6897111 0.91 CYP3A4 (0.69) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6897116 0.91 CYP3A4 (0.69) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6894352 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6894357 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6902306 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6901280 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6901756 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6901750 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1
SCHEMBL6902307 0.90 CYP3A4 (0.68) CYP3A4LMNATSHRMAPTNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115128178-B Full-automatic detection method for various steroid esters in dried blood spot sample 上海体育大学 2023-08-25 — — CN claimed
CN-115521920-B Testosterone propionate monoclonal antibody hybridoma cell strain and application thereof 江南大学 2023-06-06 — — CN claimed
CN-113134085-A Medicine for treating white lesions of vulva 四川大学华西第二医院 2021-07-20 — — CN claimed
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF VAN BOGAERT GINA (BE) 2026-01-15 — — US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 — — US disclosed
CN-118150725-A Full-automatic pretreatment system, full-automatic detection method and application of dried blood spot sample 上海体育大学 2024-06-07 — — CN disclosed
WO-2023223235-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF PURNA PHARMACEUTICALS NV (BE) 2023-11-23 — — WO disclosed
CN-113134085-A Medicine for treating white lesions of vulva 四川大学华西第二医院 2021-07-20 — — CN disclosed
US-20160209428-A1 DIAGNOSTIC AND PREDICTIVE METABOLITE PATTERNS FOR DISORDERS AFFECTING THE BRAIN AND NERVOUS SYSTEM The United States of America as represented by the Department of Veterans Affairs, Office of the General Counsel 2016-07-21 — — US disclosed
WO-2015027116-A1 DIAGNOSTIC AND PREDICTIVE METABOLITE PATTERNS FOR DISORDERS AFFECTING THE BRAIN AND NERVOUS SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-02-26 — — WO disclosed
CN-101460846-A Method for detecting modulators of membrane androgen receptor (mAR) MEDEXIS S A (GR) 2009-06-17 — — CN disclosed
US-20090104122-A1 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (mAR) AGENTS MEDEXIS S.A. (GR) 2009-04-23 — — US disclosed
EP-2008099-A2 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (MAR) AGENTS Medexis S.A. (GR) 2008-12-31 — — EP disclosed
WO-2007123682-A2 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (MAR) AGENTS MEDEXIS S.A. (GR) 2007-11-01 — — WO disclosed
US-20060292185-A1 Topical skin preparations for treatment of skin aging comprising a testosterone ester TOPIMED LTD. (IL) 2006-12-28 — — US disclosed
US-6274118-B1 INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE NORDION INTERNATIONAL INC. (CA) 2001-08-14 — — US disclosed
US-4219489-A Synthesis of steroids THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1980-08-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014080-A1 LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF NR5A1, SHBG, GNRHR CYP3A4 1458/4885LMNA 796/4885TSHR 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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