Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453725 | 0.74 | LTA4H (0.40) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL3081094 | 0.74 | LTA4H (0.40) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL9816269 | 0.74 | LTA4H (0.40) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL183720 | 0.74 | LTA4H (0.40) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL10083749 | 0.73 | LTA4H (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL11253530 | 0.73 | LTA4H (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL9541482 | 0.73 | PPARG (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL9910049 | 0.73 | LTA4H (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL2569849 | 0.73 | LTA4H (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 | |
| SCHEMBL12160201 | 0.73 | LTA4H (0.39) | LTA4HCA4TSHRKCNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399570-B2 | Functionalized polymers and improved tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20090326161-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7598322-B1 | particularly tire treads exhibiting reduced rolling resistance; a vulcanized rubbery polymer such as polybutadiene-butadiene-styrene copolymer made from living polymerization using butyllithium initiator and a tributyloxyborane as polymerization terminator | BRIDGESTONE CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |