SCHEMBL4264065

SCHEMBL4264065

CC(=O)SCc1ccc(I)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
NOS1 P29475 2/20 0.40
ACE P12821 1/20 0.38
IDO1 P14902 5/20 0.38
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
TPMT P51580 1/20 0.37
DAO P14920 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19725955 0.81 IDO1 (0.59) NOS1IDO1NOS3NOS2DAO
SCHEMBL11957418 0.81 NOS1 (0.46) NOS1IDO1NOS3NOS2TDP1
SCHEMBL10126371 0.81 IDO1 (0.51) NOS1IDO1TDP1L3MBTL1CA2
SCHEMBL6517369 0.81 IDO1 (0.59) NOS1IDO1
SCHEMBL6517363 0.79 NOS1 (0.40) NOS1IDO1NOS3NOS2TDP1
SCHEMBL14611678 0.79 IDO1 (0.57) IDO1TDP1L3MBTL1
SCHEMBL7185466 0.79 IDO1 (0.57) IDO1L3MBTL1
SCHEMBL17297115 0.79 KDM4E (0.47) NOS1IDO1NOS3NOS2
SCHEMBL241936 0.79 KMT2A (0.43) NOS1IDO1NOS3NOS2TDP1
SCHEMBL5376375 0.79 IDO1 (0.57) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 EP disclosed
US-6728129-B2 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-27 US disclosed
US-20030169618-A1 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER 2003-09-11 US disclosed
WO-2003071552-A1 MULTISTATE TRIPLE-DECKER DYADS IN THREE DISTINCT ARCHITECTURES FOR INFORMATION STORAGE APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-28 WO disclosed
WO-2001003126-A9 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV CALIFORNIA (US) 2002-08-01 WO disclosed
EP-1210714-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE The Regents of the University of California (US) 2002-06-05 EP disclosed
WO-2001003126-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-01-11 WO disclosed