SCHEMBL4264089

SCHEMBL4264089

CC(=O)CC(=O)OCCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
KDM4E B2RXH2 1/20 0.45
KDM6B O15054 1/20 0.45
KDM5C P41229 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
PHF8 Q9UPP1 1/20 0.45
KDM2A Q9Y2K7 1/20 0.45
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 3/20 0.41
SLC15A2 Q16348 1/20 0.41
SLC22A6 Q4U2R8 2/20 0.40
ADRA1A P35348 1/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
AKR1B1 P15121 1/20 0.38
FAAH O00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570629 0.90 KDM4E (0.50) TSHRKDM4EKDM6BKDM5CEGLN1
SCHEMBL5393914 0.85 TSHR (0.48) TSHRALDH1A1LMNASLC22A6NFKB1
SCHEMBL16411225 0.84 MGAM (0.55) TSHRMGAMGAASIMGAM2
SCHEMBL649327 0.84 MGAM (0.55) TSHRMGAMGAASIMGAM2
SCHEMBL28365336 0.83 LMNA (0.52) TSHRKDM6BKDM5CEGLN1PHF8
SCHEMBL28062988 0.83 MGAM (0.44) TSHRKDM4EMGAMGAASI
SCHEMBL23041373 0.82 MGAM (0.52) TSHRMGAMGAASIMGAM2
SCHEMBL4595426 0.82 MGAM (0.52) TSHRMGAMGAASIMGAM2
SCHEMBL6146968 0.82 MGAM (0.52) TSHRMGAMGAASIMGAM2
SCHEMBL650012 0.82 MGAM (0.52) TSHRMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145651-A1 SENSING SYSTEMS AND METHODS FOR HYBRID GLUCOSE AND KETONE MONITORING DEXCOM, INC. (US) 2024-07-04 WO disclosed
US-20210106039-A1 SYSTEMS AND METHODS FOR MONITORING OF BLOOD LACTATE AND TARGETING OF BLOOD LACTATE VIA NUTRITIONAL SUPPORT RUN THEM SWEET LLC 2021-04-15 US disclosed
CN-112351774-A Compositions and methods for ketone stacking of beta-hydroxybutyrate and acetoacetate 阿克塞斯全球科学有限责任公司 2021-02-09 CN disclosed
US-10888245-B2 Fat burning monitoring ONTARIO LIMITED (CA) 2021-01-12 US disclosed
US-20190320935-A1 Fat Burning Monitoring 1625986 ONTARIO LIMITED (CA) 2019-10-24 US disclosed
EP-3505167-A1 SUPPORT OF NUTRITIONAL NEEDS OF HUMAN AND OTHER PATIENTS Run Them Sweet LLC (US) 2019-07-03 EP disclosed
WO-2018085944-A1 FAT BURNING MONITORING 1625986 ONTARIO LIMITED (CA) 2018-05-17 WO disclosed
US-20090082264-A1 123 Human Secreted Proteins HUMAN GENOME SCIENCES, INC. (US) 2009-03-26 US disclosed
US-7196164-B2 Secreted protein HHTLF25 HUMAN GENOME SCIENCES, INC. (US) 2007-03-27 US disclosed
EP-1017379-A4 THERAPEUTIC COMPOSITIONS BTG INT LTD (GB) 2007-01-24 EP disclosed
US-7112668-B2 Polypeptides and nucleic acids encoded thereby CURAGEN CORPORATION (US) 2006-09-26 US disclosed
US-7105644-B2 Secreted protein HHTLF25 antibodies HUMAN GENOME SCIENCES, INC. (US) 2006-09-12 US disclosed
US-20050288241-A1 NOVEL POLYPEPTIDES AND NUCLEIC ACIDS ENCODED THEREBY CURAGEN CORPORATION 2005-12-29 US disclosed
US-20040044191-A1 123 human secreted proteins HUMAN GENOME SCIENCES, INC. 2004-03-04 US disclosed
EP-1360198-A2 NOVEL POLYPEPTIDES AND NUCLEIC ACIDS ENCODED THEREBY Curagen Corporation (US) 2003-11-12 EP disclosed
US-20030064412-A1 123 human secreted proteins FISCHER CARRIE L (US) 2003-04-03 US disclosed
US-20030022185-A1 Secreted protein HLHFP03 HUMAN GENOME SCIENCES, INC. 2003-01-30 US disclosed
WO-2002081517-A2 NOVEL POLYPEPTIDES AND NUCLEIC ACIDS ENCODED THEREBY CURAGEN CORPORATION (US) 2002-10-17 WO disclosed
EP-1017379-A1 THERAPEUTIC COMPOSITIONS BTG INTERNATIONAL LIMITED (GB) 2000-07-12 EP disclosed
WO-1998041201-A1 THERAPEUTIC COMPOSITIONS BTG INTERNATIONAL LIMITED (GB) 1998-09-24 WO disclosed