SCHEMBL4264228

SCHEMBL4264228

OCc1cncc(CO)n1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.42
PKM P14618 1/20 0.35
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
P2RX7 Q99572 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23214620 0.82
SCHEMBL11400820 0.82
SCHEMBL8447800 0.82
SCHEMBL4268319 0.77 PIM1 (0.35) PKMKDM4EPOLBRECQLPMP22
SCHEMBL23015668 0.77 IRAK4 (0.34) CCR1
SCHEMBL23538172 0.77 CCR1 (0.31) CCR1
SCHEMBL24933030 0.75 SLC5A2 (0.31) CCR1
SCHEMBL24324093 0.71 PDE10A (0.46) KDM4E
SCHEMBL7652088 0.69
SCHEMBL284256 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
US-20060160979-A1 Method for forming a crosslinked polymer by temperature control BATTELLE MEMORIAL INSTITUTE 2006-07-20 US disclosed
US-6989466-B2 Reversible crosslinked polymers, benzylic hydroxyl crosslinkers and method BATTELLE MEMORIAL INSTITUTE (US) 2006-01-24 US disclosed
US-20040014928-A1 Reversible crosslinked polymers, benzylic hydroxyl crosslinkers and method BENECKE HERMAN P (US) 2004-01-22 US disclosed
US-20030225238-A1 Reversible crosslinked polymers, benzylic hydroxyl crosslinkers and method BENECKE HERMAN P (US) 2003-12-04 US disclosed
US-6559263-B1 A polymer with a crosslinked structure having reversible crosslinks comprising one or more urethane bonds produced by the reaction of one or more benzylic hydroxyl groups and one or more isocyanate groups. BATTELLE MEMORIAL INSTITUTE 2003-05-06 US disclosed