SCHEMBL4264401

SCHEMBL4264401

CCNC(=O)Sc1ccc(-c2c3nc(c(-c4c(F)c(F)c(F)c(F)c4F)c4ccc([nH]4)c(-c4c(F)c(F)c(F)c(F)c4F)c4nc(c(-c5c(F)c(F)c(F)c(F)c5F)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.45
▸ CYCS P99999 4/20 0.44
▸ ABCG2 Q9UNQ0 1/20 0.44
▸ ENPP2 Q13822 1/20 0.41
▸ TERT O14746 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274606 0.85 ABCG2 (0.45) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4265036 0.82 ABCG2 (0.44) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4258767 0.82 ABCG2 (0.43) TOP1CYCSABCG2ENPP2TERT
SCHEMBL12733626 0.74 TOP1 (0.81) TOP1CYCSABCG2ENPP2TERT
SCHEMBL13554588 0.74 TERT (0.51) TOP1CYCSABCG2ENPP2TERT
SCHEMBL30739548 0.74 TOP1 (0.54) TOP1CYCSABCG2ENPP2TERT
SCHEMBL13309422 0.74 TERT (0.51) TOP1CYCSABCG2ENPP2TERT
SCHEMBL17996893 0.71 TOP1 (0.64) TOP1CYCSABCG2ENPP2TERT
SCHEMBL29582816 0.71 TERT (0.47) TOP1CYCSENPP2TERT
SCHEMBL29648942 0.71 TERT (0.47) TOP1CYCSENPP2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 — — US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 — — US disclosed
US-7061791-B2 High density molecular memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-13 — — US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 — — US disclosed
US-20050041494-A1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA AND NORTH CAROLINA STATE UNIVERSITY 2005-02-24 — — US disclosed
US-6381169-B1 FIXED ELECTRODES COUPLING TO STORAGE MEDIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-04-30 — — US disclosed
US-6208553-B1 High density non-volatile memory device incorporating thiol-derivatized porphyrins THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-03-27 — — US disclosed
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