Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062962 | 1.00 | CA2 (0.33) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL9995950 | 1.00 | CA2 (0.33) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL9995998 | 1.00 | CA2 (0.33) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL4053923 | 0.85 | CXCR1 (0.32) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL9995962 | 0.85 | CXCR1 (0.32) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL4052712 | 0.85 | CXCR1 (0.32) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL4052073 | 0.85 | CXCR1 (0.32) | CA2HCRTR2HCRTR1CXCR1CXCR2 | |
| SCHEMBL28588817 | 0.80 | HCRTR2 (0.40) | CA2HCRTR2 | |
| SCHEMBL13725768 | 0.80 | HCRTR2 (0.40) | CA2HCRTR2 | |
| SCHEMBL3182760 | 0.79 | HCRTR2 (0.34) | CA2HCRTR2HCRTR1CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| EP-2395005-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | Industrial Research Limited (NZ) | 2011-12-14 | — | — | EP | disclosed |
| EP-2057165-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008030119-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |