SCHEMBL4265461

SCHEMBL4265461

O=C1c2ccccc2C(=O)N1SC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 7/20 0.46
▸ LGALS1 P09382 3/20 0.46
▸ LGALS9 O00182 2/20 0.46
▸ LGALS8 O00214 1/20 0.46
▸ CA12 O43570 2/20 0.43
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CA4 P22748 2/20 0.43
▸ CA5A P35218 2/20 0.43
▸ CA7 P43166 2/20 0.43
▸ CA5B Q9Y2D0 2/20 0.43
▸ LGALS7; LGALS7B P47929 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ PKM P14618 1/20 0.40
▸ ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4265462 1.00 LGALS3 (0.46) LGALS3LGALS1LGALS9LGALS8CA12
SCHEMBL7786712 0.76 LGALS3 (0.42) LGALS3LGALS1LGALS9LGALS7; LGALS7BALDH1A1
SCHEMBL26099251 0.75 CDA (0.49) MAPT
SCHEMBL9207675 0.73 LGALS3 (0.40) LGALS3LGALS1LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL9207688 0.73 LGALS3 (0.40) LGALS3LGALS1LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL19064146 0.73 CA12 (0.44) LGALS3LGALS1LGALS9CA12CA1
SCHEMBL28367366 0.72 PTPN1 (0.49) MAPT
SCHEMBL3879383 0.72 PTPN1 (0.49) MAPT
SCHEMBL4282931 0.72 PTPN1 (0.49) MAPT
SCHEMBL3879381 0.72 PTPN1 (0.49) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10231907-B2 Compositions for improving the health and appearance of skin ALGENIST HOLDINGS, INC. (US) 2019-03-19 — — US disclosed
US-20150366791-A1 Compositions for Improving the Health and Appearance of Skin ALGENIST BRANDS LLC 2015-12-24 — — US disclosed
US-9095733-B2 Compositions for improving the health and appearance of skin SOLAZYME, INC. (US) 2015-08-04 — — US disclosed
US-8298548-B2 Compositions for improving the health and appearance of skin SOLAZYME, INC. (US) 2012-10-30 — — US disclosed
US-20120264177-A1 Compositions for Improving the Health and Appearance of Skin SOLAZYME, INC. (US) 2012-10-18 — — US disclosed
US-20090069213-A1 Compositions for Improving the Health and Appearance of Skin SOLAZYME, INC. (US) 2009-03-12 — — US disclosed
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