SCHEMBL4265572

SCHEMBL4265572

CC(C)(C)Oc1cc2ccccc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.45
AOC3 Q16853 2/20 0.44
BRD4 O60885 1/20 0.43
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
KDM4E B2RXH2 7/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
CASP3 P42574 2/20 0.41
SENP8 Q96LD8 2/20 0.41
SENP7 Q9BQF6 2/20 0.41
SENP6 Q9GZR1 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.40
FLT3 P36888 1/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10920860 0.82 FLT3 (0.40) AOC3BRD4RAB9ANPC1KDM4E
SCHEMBL7481322 0.81 KIF11 (0.45) KIF11AOC3BRD4RAB9ANPC1
SCHEMBL827599 0.78 KDM4E (0.53) AOC3BRD4RAB9ANPC1KDM4E
SCHEMBL29614783 0.78 KDM4E (0.53) AOC3BRD4RAB9ANPC1KDM4E
SCHEMBL7325746 0.77 AOC3 (0.52) AOC3BRD4RAB9ANPC1KDM4E
Hydrochloric Acid SCHEMBL7218573 0.76 KDM4E (0.51) AOC3BRD4RAB9ANPC1KDM4E
SCHEMBL10664296 0.75 KDM4E (0.43) RAB9ANPC1KDM4EMAPTHPGD
SCHEMBL28126709 0.74 KDM4E (0.46) AOC3BRD4RAB9ANPC1KDM4E
SCHEMBL29045739 0.74 FLT3 (0.46) BRD4KDM4EMAPTALDH1A1HPGD
SCHEMBL5850730 0.74 FLT3 (0.48) AOC3BRD4RAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347561-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF Bright Minds Biosciences Inc. (CA) 2024-04-10 EP disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed