Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 6/20 | 0.57 |
| ▸ | BACE1 | P56817 | 6/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266585 | 1.00 | GRIN2B (0.62) | GRIN2BMEN1KMT2ARAB9AACHE | |
| SCHEMBL5694934 | 1.00 | GRIN2B (0.62) | GRIN2BMEN1KMT2ARAB9AACHE | |
| Hydrochloric Acid SCHEMBL27637041 | 0.98 | MEN1 (0.66) | GRIN2BMEN1KMT2ARAB9AACHE | |
| SCHEMBL663239 | 0.90 | GRIN2B (0.74) | GRIN2BMEN1KMT2ARAB9AACHE | |
| SCHEMBL29577700 | 0.90 | MEN1 (0.81) | GRIN2BMEN1KMT2ARAB9AACHE | |
| Hydrochloric Acid SCHEMBL2550113 | 0.88 | MEN1 (0.78) | GRIN2BMEN1KMT2ARAB9AACHE | |
| SCHEMBL20999768 | 0.87 | GRIN2B (0.57) | GRIN2BMEN1KMT2ARAB9AACHE | |
| Methyl Alcohol SCHEMBL27513196 | 0.84 | GRIN2B (0.67) | GRIN2BMEN1KMT2ARAB9AACHE | |
| SCHEMBL3184557 | 0.84 | GRIN2B (0.67) | GRIN2BMEN1KMT2ARAB9AACHE | |
| Bicarbonate SCHEMBL11118446 | 0.82 | GRIN2B (0.65) | GRIN2BMEN1KMT2ARAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| WO-2006035967-A1 | PYRIDINE DERIVATIVES AND THEIR USE AS MEDICAMENTS FOR TREATING DISEASES RELATED TO MCH RECEPTOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | MCHR1, GPR119, MCHR2 | GRIN2B 178/4885MEN1 1056/4885KMT2A 818/4885 |
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | GRIN2B 194/4885MEN1 2494/4885KMT2A 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.