Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255598 | 0.84 | MCHR1 (0.45) | MCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL4262300 | 0.81 | MCHR1 (0.58) | MCHR1ADRA2AADRA1AHRH1NPY5R | |
| SCHEMBL4262303 | 0.81 | MCHR1 (0.58) | MCHR1ADRA2AADRA1AHRH1NPY5R | |
| Trifluoroacetic Acid SCHEMBL4267018 | 0.80 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHRH1NPY5R | |
| Trifluoroacetic Acid SCHEMBL4267015 | 0.80 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHRH1NPY5R | |
| SCHEMBL4259743 | 0.79 | MCHR1 (0.73) | MCHR1ADRA2AADRA1AHRH1EPHX2 | |
| SCHEMBL4259739 | 0.79 | MCHR1 (0.73) | MCHR1ADRA2AADRA1AHRH1EPHX2 | |
| SCHEMBL6464232 | 0.79 | MCHR1 (0.51) | MCHR1ADRA2ASYKADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL4263476 | 0.79 | MCHR1 (0.72) | MCHR1ADRA2AADRA1AHRH1EPHX2 | |
| Hydrochloric Acid SCHEMBL4263483 | 0.79 | MCHR1 (0.72) | MCHR1ADRA2AADRA1AHRH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | MCHR1 3/4885GALR2 485/4885GALR1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.