SCHEMBL4267254

SCHEMBL4267254

c1cc(-c2nnn[nH]2)ncc1C12CCCN(CC1)C2.c1nc(-c2ccc(C34CCCN(CC3)C4)cn2)n[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1483337 0.90
SCHEMBL1483338 0.89
Bromide SCHEMBL1483232 0.88
SCHEMBL1483678 0.77 KDM4E (0.38)
SCHEMBL1483304 0.72
SCHEMBL1483313 0.71 ROCK1 (0.36)
Hydrochloric Acid SCHEMBL1484299 0.70 ROCK1 (0.35)
SCHEMBL1483655 0.69
SCHEMBL1482815 0.69 ALOX5AP (0.41)
SCHEMBL1483251 0.69 ALOX5AP (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915375-B1 DERIVATIVES OF 5-PYRIDINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2009-10-07 EP claimed