Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656799 | 1.00 | AR (0.60) | ARKCNH2 | |
| SCHEMBL4268059 | 1.00 | AR (0.60) | ARKCNH2 | |
| SCHEMBL13656783 | 0.84 | AR (0.62) | ARKCNH2 | |
| SCHEMBL13656800 | 0.84 | AR (0.64) | ARKCNH2 | |
| SCHEMBL13656779 | 0.84 | AR (0.62) | ARKCNH2 | |
| SCHEMBL13656798 | 0.84 | AR (0.69) | ARKCNH2 | |
| SCHEMBL4268107 | 0.84 | AR (0.62) | ARKCNH2 | |
| SCHEMBL4268103 | 0.84 | AR (0.62) | ARKCNH2 | |
| SCHEMBL4276039 | 0.78 | AR (0.77) | ARKCNH2 | |
| SCHEMBL4276042 | 0.78 | AR (0.77) | ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605152-B2 | 17-hydroxy-4-aza-androstan-3-ones as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20050107416-A1 | 17-hydroxy 4-aza androstan -3-ones as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107416-A1 | 17-hydroxy 4-aza androstan -3-ones as androgen receptor modulators | SHBG, CYP19A1, NR5A1 | AR 6/4885KCNH2 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.