⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699855 | 0.86 | — | — | |
| SCHEMBL7947549 | 0.86 | — | — | |
| SCHEMBL7945581 | 0.86 | — | — | |
| SCHEMBL9644963 | 0.84 | — | — | |
| SCHEMBL8954690 | 0.78 | — | — | |
| SCHEMBL7945955 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL315273 | 0.74 | PDE4A (0.32) | — | |
| SCHEMBL313770 | 0.74 | PDE4A (0.32) | — | |
| SCHEMBL3922056 | 0.74 | PDE4A (0.32) | — | |
| Hydrochloric Acid SCHEMBL5866744 | 0.73 | PDE4A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084016-B2 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090041661-A1 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-12 | — | — | US | disclosed |
| US-7449171-B2 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1483399-B1 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | UNIV CALIFORNIA (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1483399-A4 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | UNIV CALIFORNIA (US) | 2006-07-19 | — | — | EP | disclosed |
| EP-1483399-A2 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | The Regents of the University of California (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030228259-A1 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-12-11 | — | — | US | disclosed |
| WO-2003068919-A2 | NON-INVASIVE METHOD FOR MEASURING RATES OF BIOSYNTHESIS OF BIOLOGICAL MOLECULES BY LABEL INCORPORATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-08-21 | — | — | WO | disclosed |