SCHEMBL426995

SCHEMBL426995

CN(C)CC([NH])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425021 0.75
SCHEMBL6050286 0.73
SCHEMBL8382912 0.73
SCHEMBL2111443 0.72 TDP1 (0.35)
SCHEMBL8382703 0.69 LMNA (0.37)
SCHEMBL7055782 0.69
SCHEMBL441470 0.69
SCHEMBL21778 0.69
SCHEMBL1275724 0.69
SCHEMBL716553 0.69 TDP1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 882 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498716-B1 SULFONYL BEARING THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATION AS ANTI-CANCER AGENT UNIV XIAMEN (CN) 2024-04-17 EP claimed
US-11767295-B2 Isoindole derivative TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) 2023-09-26 US claimed
US-20230113011-A1 METHODS OF TREATING ILLNESSES CAUSED BY CORONAVIRUS, SWINE FLU AND AVIAN FLU CMTX BIOTECH INC. (US) 2023-04-13 US claimed
CN-109721531-B Novel liposome kinase inhibitor 中国科学院合肥物质科学研究院 2022-07-29 CN claimed
CN-112107568-B Diaryl amide compound and application thereof 北京龙嘉博创医药科技有限公司 2022-03-25 CN claimed
US-20210155590-A1 ISOINDOLE DERIVATIVE TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) 2021-05-27 US claimed
EP-3782983-A1 ISOINDOLE DERIVATIVE Tianjin Hemay Pharmaceutical Co., Ltd. (CN) 2021-02-24 EP claimed
CN-109575045-B Thienopyrimidine compound, preparation method thereof, medicinal composition and application thereof 南京红云生物科技有限公司 2021-02-12 CN claimed
US-20200207779-A2 THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF Hongyun Biotech Co., Ltd. (CN) 2020-07-02 US claimed
WO-2019201255-A1 ISOINDOLE DERIVATIVE 天津合美医药科技有限公司 2019-10-24 WO claimed
US-5811553-A TREATMENT OF NEURODEGENERATIVE DISORDERS, PULMONARY DISORDERS SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) 1998-09-22 US claimed
EP-0804419-A1 QUINOLINE DERIVATIVES AS TACHYKININ NK 3 RECEPTOR ANTAGONISTS SmithKline Beecham Farmaceutici S.p.A. (IT) 1997-11-05 EP claimed
EP-0790986-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1997-08-27 EP claimed
WO-1996040686-A1 HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS ABBOTT LABORATORIES (US) 1996-12-19 WO claimed
WO-1996015118-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1996-05-23 WO claimed
WO-1995032948-A1 QUINOLINE DERIVATIVES AS TACHYKININ NK3 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) 1995-12-07 WO claimed
US-5225528-A Controlling premature labor MERCK & CO., INC. (US) 1993-07-06 US claimed
EP-0444898-A1 Cyclic hexapeptide oxytocin antagonists MERCK & CO. INC. (US) 1991-09-04 EP claimed
EP-0213326-B1 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1991-03-06 EP claimed
EP-0212588-B1 Saturated cycloalkyl [b] pyrrole-1(2H)-acetic acid amides and derivatives thereof WARNER-LAMBERT COMPANY (US) 1989-12-06 EP claimed