⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33790 | 0.71 | — | — | |
| SCHEMBL30441407 | 0.60 | — | — | |
| SCHEMBL3762424 | 0.58 | — | — | |
| SCHEMBL30476130 | 0.55 | — | — | |
| SCHEMBL9774599 | 0.55 | — | — | |
| SCHEMBL17744967 | 0.52 | — | — | |
| SCHEMBL3321079 | 0.51 | — | — | |
| SCHEMBL7118357 | 0.51 | — | — | |
| SCHEMBL9774597 | 0.50 | — | — | |
| SCHEMBL22193800 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387546-A1 | Methods For Treating And/Or Preventing Hypersomnias | UNIVERSITE DE LAUSANNE (CH) | 2022-12-08 | — | — | US | disclosed |
| CN-114829386-A | Method for treating and/or preventing hypersomnia | 洛桑大学 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021078631-A1 | METHODS FOR TREATING AND/OR PREVENTING HYPERSOMNIAS | Université de Lausanne (CH) | 2021-04-29 | — | — | WO | disclosed |
| EP-3812396-A1 | METHODS FOR TREATING AND/OR PREVENTING HYPERSOMNIAS | Université de Lausanne (CH) | 2021-04-28 | — | — | EP | disclosed |
| WO-2017207623-A1 | MIRNA AS BIOMARKERS AND REGULATORS OF CANCER STEM CELLS | Université de Lausanne (CH) | 2017-12-07 | — | — | WO | disclosed |
| US-9724404-B2 | HPV particles and uses thereof | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-08-08 | — | — | US | disclosed |
| US-20170175112-A1 | MIR-21-3P INHIBITORS IN SKIN DISORDERS | UNIVERSITE DE LAUSANNE (CH) | 2017-06-22 | — | — | US | disclosed |
| EP-3105330-A1 | MiR-21-3p INHIBITORS IN SKIN DISORDERS | Université de Lausanne (CH) | 2016-12-21 | — | — | EP | disclosed |
| US-9334311-B2 | Chimeric OspA genes, proteins and methods of use thereof | BAXALTA INCORPORATED (US) | 2016-05-10 | — | — | US | disclosed |
| US-9139835-B2 | Nucleic acid aptamers | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-09-22 | — | — | US | disclosed |
| US-20090209045-A1 | SCREENING ASSAY | GENOPHRENIX LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| US-20090023678-A1 | Amino Acid Vitamin Ester Compositions for Controlled Delivery of Pharmaceutically Active Compounds | IDEXX LABORATORIES, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| US-20060155113-A1 | drug screening for identification of agents which modulate the activity of a DNA replication protein as a target for intervention in cancer therapy; carcinoma, adenocarcinoma, lymphoma or leukemia; liver, lung or skin cancer; use of a Ciz1 nucleotide or polypeptide sequence | CIZZLE BIOTECHNOLOGY LIMITED (GB) | 2006-07-13 | — | — | US | disclosed |
| US-20060121462-A1 | Receptor and screening methods | SHEFFIELD, UNIVERSITY OF (GB) | 2006-06-08 | — | — | US | disclosed |
| US-7029892-B1 | Serine threonine kinase member, h2520-59 | AMGEN, INC. (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060067926-A1 | Novel serine threonine kinase member, h2520-59 | AMGEN INC. (US) | 2006-03-30 | — | — | US | disclosed |
| US-6881542-B1 | Serine threonine kinase member, h2520-59 | AMGEN INC. (US) | 2005-04-19 | — | — | US | disclosed |
| EP-0558634-A4 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES INC (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0558634-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009705-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |