SCHEMBL4270604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4269852	0.89	KDM4E (0.53)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL17243832	0.89	TSHR (0.53)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4280199	0.86	TSHR (0.41)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL19066427	0.86	TSHR (0.41)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4277052	0.85	MAPK1 (0.50)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4284397	0.84	TSHR (0.44)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4271756	0.82	TSHR (0.48)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4270615	0.82	SMPD1 (0.48)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4274912	0.81	PDE4A (0.48)	TSHRMAPTKDM4EALDH1A1HSD17B10
	SCHEMBL4278443	0.81	KDM4E (0.47)	TSHRMAPTKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.