SCHEMBL4277052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271199	0.89	MAPK1 (0.48)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA
	SCHEMBL4284149	0.87	XDH (0.44)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA
	SCHEMBL4271902	0.86	KDM4E (0.44)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA
	Hydrochloric Acid SCHEMBL30484592	0.86	XDH (0.43)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA
	SCHEMBL4282936	0.85	FPR2 (0.44)	MAPK1ALDH1A1HPGDSMN1; SMN2NPC1
	SCHEMBL4270604	0.85	TSHR (0.53)	ALDH1A1HPGDSMN1; SMN2LMNANPC1
	SCHEMBL4271339	0.85	KDM4E (0.53)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA
	SCHEMBL29204611	0.84	ALDH1A1 (0.44)	ALDH1A1KDM4EABCB1ABCC1
	SCHEMBL30484435	0.84	ALDH1A1 (0.44)	ALDH1A1KDM4EABCB1ABCC1
	SCHEMBL4278843	0.83	MAPK1 (0.48)	MAPK1ALDH1A1HPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.