Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515818 | 0.90 | CYP1A2 (0.55) | TDP1CYP1A2ALDH1A1CTSBFBP1 | |
| SCHEMBL16990735 | 0.90 | CYP1A2 (0.55) | TDP1CYP1A2ALDH1A1CTSBFBP1 | |
| SCHEMBL28012828 | 0.83 | TDP1 (0.47) | TDP1CYP1A2ALDH1A1CTSBFBP1 | |
| SCHEMBL74692 | 0.82 | CYP1A2 (0.62) | CYP1A2ALDH1A1HPGDTSHRL3MBTL1 | |
| SCHEMBL29564952 | 0.82 | TDP1 (0.76) | TDP1CYP1A2MAPTHPGDAKR1B1 | |
| SCHEMBL69234 | 0.82 | TDP1 (0.76) | TDP1CYP1A2MAPTHPGDAKR1B1 | |
| SCHEMBL4388496 | 0.81 | GPR35 (0.53) | TDP1CYP1A2ALDH1A1GPR35TSHR | |
| SCHEMBL3953258 | 0.81 | GPR35 (0.60) | TDP1CYP1A2ALDH1A1GPR35TSHR | |
| Hydrochloric Acid SCHEMBL2530464 | 0.81 | CYP1A2 (0.60) | CYP1A2ALDH1A1HPGDTSHRL3MBTL1 | |
| SCHEMBL27861233 | 0.81 | CYP1A2 (0.60) | CYP1A2ALDH1A1HPGDTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | NR1H3, NR1H2, NR1H4 | TDP1 4345/4885CYP1A2 117/4885ALDH1A1 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.