Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.61 |
| ▸ | CNR2 | P34972 | 10/20 | 0.61 |
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585227 | 0.84 | ESR1 (0.57) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL2692670 | 0.80 | ESR1 (0.80) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL8024041 | 0.78 | ESR1 (0.63) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL1205246 | 0.76 | CNR2 (1.00) | CNR1CNR2ESR1ESR2CYP3A4 | |
| Orthocresol SCHEMBL8038638 | 0.76 | ESR1 (0.59) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL728277 | 0.75 | ESR1 (0.44) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL647966 | 0.75 | ESR1 (0.59) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL1206833 | 0.74 | CNR1 (1.00) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL9453752 | 0.74 | ESR1 (0.56) | CNR1CNR2ESR1ESR2CYP3A4 | |
| SCHEMBL565312 | 0.74 | ESR1 (0.57) | CNR1CNR2ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131655-A2 | TRI-ARYL/HETEROAROMATIC CANNABINOIDS AND USE THEREOF | The University of Tennessee Research Foundation (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008109027-A2 | TRI-ARYL/HETEROAROAROMATIC CANNABINOIDS AND USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2008-09-12 | — | — | WO | disclosed |