Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938956 | 0.82 | ESR1 (0.39) | ESR1ALDH1A1HPGDCYP3A4ALOX15 | |
| SCHEMBL1020689 | 0.80 | ESR1 (0.58) | ESR1ALDH1A1ESR2RAB9ASMN1; SMN2 | |
| SCHEMBL11109926 | 0.78 | CNR1 (0.34) | RAB9ASMN1; SMN2NPC1ATMCNR1 | |
| SCHEMBL728270 | 0.77 | CNR2 (0.38) | RAB9ASMN1; SMN2NPC1ATMCNR1 | |
| SCHEMBL1005238 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL12681356 | 0.77 | LMNA (0.42) | ALDH1A1HPGDHSD17B10TSHRTDP1 | |
| SCHEMBL12286646 | 0.76 | ESR1 (0.54) | ESR1ALDH1A1HPGDCYP3A4ALOX15 | |
| SCHEMBL296464 | 0.76 | BACE1 (0.49) | ESR1ALDH1A1HPGDCYP3A4ALOX15 | |
| SCHEMBL14659277 | 0.76 | CNR1 (0.47) | ESR1ALDH1A1HPGDCYP3A4ALOX15 | |
| SCHEMBL4270966 | 0.75 | CNR1 (0.61) | ESR1ALDH1A1HPGDCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660560-B1 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-03-23 | — | — | EP | claimed |
| JP-4768635-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| EP-1546249-B1 | FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-03-16 | — | — | EP | claimed |
| US-7714095-B2 | Phase transfer catalyzed method for preparation of polyetherimides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-11 | — | — | US | claimed |
| JP-2009521548-A | — | — | 2009-06-04 | — | — | JP | claimed |
| EP-1660556-B1 | COPOLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-05-13 | — | — | EP | claimed |
| EP-1989246-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-12 | — | — | EP | claimed |
| EP-1966320-A2 | HIGH GLASS TRANSITION TEMPERATURE THERMOPLASTIC ARTICLES | General Electric Company (US) | 2008-09-10 | — | — | EP | claimed |
| EP-1963433-A2 | ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS | General Electric Company (US) | 2008-09-03 | — | — | EP | claimed |
| EP-1963432-A1 | EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS | General Electric Company (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2005021477-A2 | METHOD FOR MAKING SALTS OF HYDROXY-SUBSTITUTED HYDROCARBONS | GENERAL ELECTRIC COMPANY (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050049390-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | claimed |
| US-6844071-B1 | Multilayer articles comprising polycarbonate and polypropylene and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 2005-01-18 | — | — | US | claimed |
| US-6713598-B2 | FLAME RETARDANT WITH SPECIFIED MOLECULAR WEIGHT AND SOFTENING TEMPERATURE; REACTING PHOSPHORUS OXYHALIDE WITH HYDROXYAROMATIC COMPOUND, REACTING ARYLDIHALOPHOSPHATE WITH DIHYDROXYAROMATIC, THEN WITH HYDROXYAROMATIC | GENERAL ELECTRIC COMPANY | 2004-03-30 | — | — | US | claimed |
| US-20040044134-A1 | METHOD TO MAKE A SOLID POLYMERIC PHOSPHATE AND RESINOUS COMPOSITIONS CONTAINING IT | GENERAL ELECTRIC COMPANY | 2004-03-04 | — | — | US | claimed |
| WO-2004016685-A2 | FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2004-02-26 | — | — | WO | claimed |
| US-20040034132-A1 | Flame retardant resinous compositions and method | GENERAL ELECTRIC COMPANY | 2004-02-19 | — | — | US | claimed |
| US-20040014934-A1 | Method for the production of polyestercarbonates | GENERAL ELECTRIC COMPANY | 2004-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | HDHD5, SHH, HAAO | ESR1 2614/4885ALDH1A1 2467/4885HPGD 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.