SCHEMBL427134

SCHEMBL427134

CN(CCC(Oc1ccc(-c2ccccc2)cc1)c1ccc(F)cc1)CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 20/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPT P10636 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
SLC6A5 Q9Y345 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1052569 1.00 SLC6A9 (1.00) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
Hydrochloric Acid SCHEMBL375237 0.99 SLC6A9 (1.00) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL26840802 0.92 SLC6A9 (0.85) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL26840804 0.92 SLC6A9 (0.85) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6823016 0.89 SLC6A9 (0.80) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6826926 0.88 SLC6A9 (0.82) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6567625 0.87 SLC6A9 (0.77) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6826140 0.86 SLC6A9 (0.75) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6565594 0.84 SLC6A9 (0.73) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL7214281 0.84 SLC6A9 (0.73) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12388726-B2 Synchronized wireless network slicing T-MOBILE INNOVATIONS LLC (US) 2025-08-12 US claimed
CN-120146644-A Two-dimensional irregular leather layout method with defects and computer readable storage medium 杭州电子科技大学 2025-06-13 CN claimed
CN-114449606-B Forwarding path method of reliable virtual network 武汉船舶通信研究所(中国船舶重工集团公司第七二二研究所) 2025-06-13 CN claimed
US-20250175399-A1 SYNCHRONIZED WIRELESS NETWORK SLICING T-MOBILE INNOVATIONS LLC 2025-05-29 US claimed
EP-4561002-A1 SYNCHRONIZED WIRELESS NETWORK SLICING T-Mobile Innovations LLC (US) 2025-05-28 EP claimed
CN-119993360-A Use of chronic inflammation complex index or 3C score in prognosis prediction system for patients with stage II-III colorectal cancer 南昌大学第二附属医院 2025-05-13 CN claimed
CN-119574036-A Water surface aircraft cabin section water-in test device and test method 中国特种飞行器研究所 2025-03-07 CN claimed
CN-119397478-A Fault diagnosis system and method for autonomous berthing-off close-range target and obstacle sensing system 江苏科技大学 2025-02-07 CN claimed
CN-118378740-B Method, system, equipment and medium for calculating automatic falling position of manual jacking 上海方菱计算机软件有限公司 2024-11-22 CN claimed
EP-4416954-A1 5GC SERVICE BASED ARCHITECTURE OPTIMIZATION OF INITIAL SELECTION IN ROAMING Telefonaktiebolaget LM Ericsson (publ) (SE) 2024-08-21 EP claimed
CN-114449606-A Forwarding path method of reliable virtual network 武汉船舶通信研究所(中国船舶重工集团公司第七二二研究所) 2022-05-06 CN claimed
CN-113971690-A End-to-end three-dimensional point cloud registration method based on deep learning 燕山大学 2022-01-25 CN claimed
US-9504665-B2 High-dose glycine as a treatment for obsessive-compulsive disorder and obsessive-compulsive spectrum disorders CLEVELAND W LOUIS (US) 2016-11-29 US claimed
US-9415030-B2 High-dose glycine as a treatment for obsessive-compulsive disorder and obsessive-compulsive spectrum disorders CLEVELAND W LOUIS (US) 2016-08-16 US claimed
US-8604080-B2 High dose glycine as a treatment for obsessive-compulsive disorder and obsessive compulsive spectrum disorders CLEVELAND W LOUIS (US) 2013-12-10 US claimed
US-20130251635-A1 HIGH-DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE-COMPULSIVE SPECTRUM DISORDERS CLEVELAND W LOUIS (US) 2013-09-26 US claimed
US-20100113598-A1 HIGH DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE COMPULSIVE SPECTRUM DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) 2010-05-06 US claimed
US-7670838-B2 Coupling of excitation and neurogenesis in neural stem/progenitor cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-03-02 US claimed
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 WO claimed
WO-2008100727-A2 HIGH-DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE-COMPULSIVE SPECTRUM DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2008-08-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130251635-A1 HIGH-DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE-COMPULSIVE SPECTRUM DISORDERS SLC1A2, GRIN2D, SLC7A11 SLC6A9 34/4885ALDH1A1 1140/4885CYP2D6 594/4885
US-20100113598-A1 HIGH DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE COMPULSIVE SPECTRUM DISORDERS SLC1A2, GRIN2D, SLC7A11 SLC6A9 39/4885ALDH1A1 1592/4885CYP2D6 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.