⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14352518 | 0.94 | — | — | |
| SCHEMBL831131 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL122550 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL15467307 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL22037 | 0.76 | — | — | |
| SCHEMBL14534464 | 0.76 | — | — | |
| SCHEMBL1047397 | 0.75 | — | — | |
| SCHEMBL18107133 | 0.72 | — | — | |
| SCHEMBL7120115 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL6323393 | 0.72 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018030-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | VALO HEALTH, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| CN-118201924-A | Heterocyclic compounds and their use | 万特斯治疗美国公司 | 2024-06-14 | — | — | CN | disclosed |
| US-12006332-B2 | Aminopyrimidine derivatives as phosphatidylinositol phosphate kinase inhibitors | HIBERCELL, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240158415-A1 | AMINOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | HIBERCELL INC (US) | 2024-05-16 | — | — | US | disclosed |
| EP-4351558-A1 | COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES | Ness Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2024073133-A1 | PYRIDAZIN-3(2H)-ONE AND PYRIDIN-2(1H)-ONE PARP INHIBITOR COMPOUNDS | AZKARRA THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| US-11932650-B2 | Potent agelastatin derivatives as modulators for cancer invasion and metastasis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-03-19 | — | — | US | disclosed |
| EP-4335512-A2 | CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | HiberCell, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11919839-B2 | Alpha-cinnamide compounds and compositions as HDAC8 inhibitors | VALO HEALTH, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-6703182-B1 | PHOTOPOLYMERISABLE COMPOSITIONS COMPRISING SAID COMPOUNDS AND USE OF THE COMPOUNDS AS LATENT ACIDS, WHICH CAN BE ACTIVATED BY IRRADIATION WITH LIGHT | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-03-09 | — | — | US | disclosed |
| EP-0842978-B1 | Resin composition and multilayered structure | KURARAY CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-20020128391-A1 | Resin composition and multilayered structure | KURARAY CO. LTD (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6388007-B1 | ETHYLENE-ALPHA-OLEFIN COPOLYMER | KURARAY CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1105373-A1 | UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS | Ciba SC Holding AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010972-A1 | NEW UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-02 | — | — | WO | disclosed |
| EP-0842978-A2 | Resin composition and multilayered structure | KURARAY CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0207598-B1 | PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4777184-A | ANTICOAGULANT, ANTIULCER AGENT | SANKYO COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0207598-A2 | Prostaglandin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |