Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534956 | 1.00 | DRD2 (0.38) | DRD2DRD1L3MBTL3DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL6952787 | 0.97 | DRD2 (0.36) | DRD2DRD1L3MBTL3DRD4DRD3 | |
| Methyl Alcohol SCHEMBL27505925 | 0.95 | DRD2 (0.39) | DRD2DRD1L3MBTL3DRD4DRD3 | |
| Ethylene SCHEMBL7146039 | 0.95 | DRD2 (0.35) | DRD2DRD1L3MBTL3DRD4DRD3 | |
| SCHEMBL6957732 | 0.91 | TRIM24 (0.39) | DRD2DRD1L3MBTL3DRD4DRD3 | |
| SCHEMBL3201704 | 0.84 | — | — | |
| Methyl Alcohol SCHEMBL28429897 | 0.80 | DRD2 (0.46) | DRD2DRD1DRD4DRD3CHRM3 | |
| SCHEMBL5586410 | 0.77 | DRD2 (0.42) | DRD2DRD4DRD3CHRM3CHRM2 | |
| SCHEMBL21047716 | 0.74 | TRIM24 (0.35) | TRIM24TRIM33ESR2ALDH1A1 | |
| SCHEMBL7323210 | 0.74 | DRD3 (0.38) | DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433638-A | Rubber blanket cleaning agent and preparation method and application thereof | 中山市富日印刷材料有限公司 | 2022-12-06 | — | — | CN | claimed |
| US-20260098032-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS INC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-3950682-B1 | PREPARATION METHOD FOR AMIDE COMPOUNDS AND USE THEREOF IN MEDICAL FIELD | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO LTD (CN) | 2026-02-11 | — | — | EP | disclosed |
| EP-4663640-A1 | XANTHINE COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-12-17 | — | — | EP | disclosed |
| US-12473298-B2 | Amide compounds, preparation method therefor, and use thereof in the medical field | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| EP-4644387-A2 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12428406-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2025-09-30 | — | — | US | disclosed |
| EP-4603480-A1 | INDOLE PHTHALOCYANINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN TUMOR DIAGNOSIS IMAGING | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-08-20 | — | — | EP | disclosed |
| CN-119968361-A | Compounds targeting p 53Y 220 mutants | 北京加科思新药研发有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119768391-A | Indole phthalocyanine compound, preparation method thereof and application thereof in tumor diagnostic imaging | 江苏亚虹医药科技股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| US-4290958-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-09-22 | — | — | US | disclosed |
| US-4288623-A | 1-Aryl-4-amino-cyclohexan-1-ols | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0027522-A1 | Spiro(cyclohexane-1,1'(3'H)-isobenzofuran)s, processes and intermediates for their preparation and pharmaceutical compositions containing them | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4226867-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |
| US-3931223-A | 3-(Dimethylamino)-1,2,3,4,8,9-hexahydro-1H[1]benzazepino[1,2,3-k,j]carbazole | STERLING DRUG INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473298-B2 | Amide compounds, preparation method therefor, and use thereof in the medical field | EZH2, IKZF2, EZH1 | DRD2 4795/4885DRD1 4827/4885L3MBTL3 3192/4885 |
| US-12428406-B2 | Methods and compounds for restoring mutant p53 function | TP53, TP53BP1, KRAS | DRD2 4653/4885DRD1 4672/4885L3MBTL3 188/4885 |
| US-20260098032-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | TP53, TP53BP1, MDM2 | DRD2 4036/4885DRD1 3950/4885L3MBTL3 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.