SCHEMBL4272397

SCHEMBL4272397

CCCC[CH]CCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.57
F3 P13726 1/20 0.57
AKR1B1 P15121 1/20 0.54
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
FABP4 P15090 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4273684 0.93 PPARG (0.61) F7F3AKR1B1GPR84PPARG
SCHEMBL28317229 0.91 PPARG (0.64) F7F3GPR84PPARGPPARD
SCHEMBL297328 0.91 PPARG (0.64) F7F3GPR84PPARGPPARD
SCHEMBL28172819 0.91 PPARG (0.64) F7F3GPR84PPARGPPARD
SCHEMBL11253604 0.91 F7 (0.63) F7F3AKR1B1GPR84PPARG
SCHEMBL5695667 0.89 PPARG (0.62) F7F3GPR84PPARGPPARD
SCHEMBL15367506 0.86 F7 (0.77) F7F3GPR84PPARGPPARD
SCHEMBL4270636 0.85
SCHEMBL7784335 0.84 PPARG (0.73) F7F3AKR1B1GPR84PPARG
SCHEMBL7786847 0.84 TOP1 (0.70) F7F3AKR1B1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605263-B2 Fluorescent naphthalene-1,4,5,8-tetracarboxylic bisimides with an electron-donating substituent on the nucleus INFINEON TECHNOLOGIES AG (DE) 2009-10-20 US disclosed
EP-1313735-B1 LIQUID CRYSTALLINE 3,4:9,10-PERYLENETETRACARBOXYLIC ACID DIIMIDES BASF SE (DE) 2008-04-23 EP disclosed
US-6806368-B2 FOR ELECTRONIC, OPTOELECTRONIC AND PHOTONIC APPLICATIONS, FOR COLORATION OF MACROMOLECULAR ORGANIC AND OF INORGANIC MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2004-10-19 US disclosed
US-20030181721-A1 Liquid crystalline 3,4:9,10-perylenetetacarbocylic acid diimides BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 US disclosed
US-20030153005-A1 Fluorescent naphthalene -1,4,5,8-tetracarboxylic bisimides with an electron-donating substituent on the nucleus POLARIS INNOVATIONS LIMITED (IE) 2003-08-14 US disclosed
EP-0873342-B1 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES BASF AG (DE) 2003-06-04 EP disclosed
EP-1313735-A1 LIQUID CRYSTALLINE 3,4:9,10-PERYLENETETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2003-05-28 EP disclosed
WO-2002014318-A1 LIQUID CRYSTALLINE 3,4:9,10-PERYLENETETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-02-21 WO disclosed
US-6326494-B1 LASER DYES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6184378-B1 PIGMENTS, LASER DYES AND PRECURSORS FOR PREPARING FLUORESCENT DYES, POLYMERIC COLORANTS, BASF AKTIENGESELLSCHAFT (DE) 2001-02-06 US disclosed
US-6143905-A REACTING 1,7-DIBROMOPERYLENE-3,4,9,10-TETRACARBOXYLIC DIANHYDRIDE OR TETRACARBOXYLIC ACID IN PRESENCE OF APROTIC SOLVENT WITH A PRIMARY AMINE TO FORM DIIMIDE, REACTING DIIMIDE WITH AROMATIC ALOCHOL OR THIOL, AND HYDROLYZING BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
EP-0869959-B1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AG (DE) 2000-05-17 EP disclosed
US-6063181-A 1,7-disubstituted perylene-3,4,9, 10-tetracarboxylic acids, their dianhydrides and diimides of said acids BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
EP-0873342-A1 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
EP-0869959-A1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AKTIENGESELLSCHAFT (DE) 1998-10-14 EP disclosed
WO-1997022607-A1 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-06-26 WO disclosed
WO-1997022608-A1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AKTIENGESELLSCHAFT (DE) 1997-06-26 WO disclosed
EP-0338723-A1 Novel compounds BEECHAM GROUP PLC (GB) 1989-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153005-A1 Fluorescent naphthalene -1,4,5,8-tetracarboxylic bisimides with an electron-donating substituent on the nucleus H1-4, H1-3, H1-5 F7 3346/4885F3 2270/4885AKR1B1 1643/4885
US-20030181721-A1 Liquid crystalline 3,4:9,10-perylenetetacarbocylic acid diimides CCR9, CLTA, HAO2 F7 1753/4885F3 1692/4885AKR1B1 3418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.