SCHEMBL4272425

SCHEMBL4272425

CCN(CC)c1cc2ccccc2[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.44
AOC3 Q16853 2/20 0.44
BRD4 O60885 1/20 0.43
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 2/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FLT3 P36888 1/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6039585 0.85 KDM4E (0.43) KDM4EALDH1A1MAPTLMNACYP1A2
SCHEMBL8609404 0.81 KDM4E (0.45) KDM4EALDH1A1MAPTLOXL2AOC3
SCHEMBL3365468 0.78 AOC3 (0.48) KDM4EALDH1A1MAPTCYP1A2LOXL2
SCHEMBL5449822 0.78 KDM4E (0.45) KDM4EALDH1A1MAPTLMNACYP1A2
SCHEMBL28593629 0.77 AOC3 (0.52) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL3393557 0.77 LOXL2 (0.41) KDM4EALDH1A1MAPTLMNALOXL2
SCHEMBL7321937 0.76 MEN1 (0.49) KDM4EALDH1A1MAPTTSHRMEN1
SCHEMBL28599651 0.75 BRD4 (0.54) KDM4EALDH1A1MAPTLMNACYP1A2
SCHEMBL28898704 0.74 NPC1 (0.47) KDM4EALDH1A1MAPTLOXL2AOC3
SCHEMBL16491461 0.74 HTR2C (0.40) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed