SCHEMBL4272803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280624	1.00	KCNH2 (0.56)	KCNH2CACNA1IKDM4EALDH1A1CACNA1G
	SCHEMBL4282719	0.95	KCNH2 (0.50)	KCNH2CACNA1IKDM4EALDH1A1CACNA1G
	SCHEMBL4277715	0.92	KCNH2 (0.59)	KCNH2CACNA1ICACNA1GCACNA1HWNT3
	SCHEMBL13569700	0.91	KCNH2 (0.45)	KCNH2CACNA1IKDM4EALDH1A1CBX7
	SCHEMBL4269237	0.88	KCNH2 (0.64)	KCNH2CACNA1ICACNA1GCACNA1HCCR2
	SCHEMBL19112606	0.87	CACNA1I (0.42)	KCNH2CACNA1IKDM4EALDH1A1CACNA1G
	SCHEMBL4271313	0.87	KCNH2 (0.52)	KCNH2CACNA1IALDH1A1CACNA1GCACNA1H
	SCHEMBL13569758	0.86	KDM4E (0.41)	KCNH2CACNA1IKDM4EALDH1A1CACNA1G
	SCHEMBL4274233	0.85	KCNH2 (0.62)	KCNH2CACNA1ICACNA1GCACNA1HCCR2
	SCHEMBL4279329	0.85	KCNH2 (0.62)	KCNH2CACNA1ICACNA1GCACNA1HCCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.