SCHEMBL4272880

SCHEMBL4272880

C(=C(c1ccccc1)c1ccccc1)c1ccccc1.[Sb]

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.71
CYP19A1 P11511 3/20 0.68
CYP11B2 P19099 2/20 0.68
PTGS2 P35354 4/20 0.57
ESR2 Q92731 2/20 0.52
AKR1C1 Q04828 1/20 0.52
CYP2D6 P10635 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
PRMT1 Q99873 1/20 0.47
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55433 0.97 ESR1 (0.74) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL30366689 0.95 ESR1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL4272869 0.95 ESR1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
Bromide SCHEMBL28733230 0.95 ESR1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
Phosphine SCHEMBL28461311 0.95 ESR1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
Hydrochloric Acid SCHEMBL28642233 0.95 ESR1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL4612465 0.95 ESR1 (0.78) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL2121142 0.92 CYP19A1 (0.71) ESR1CYP19A1CYP11B2PTGS2ESR2
(Z)-1,2-Diphenylethene SCHEMBL16874404 0.90 ESR1 (0.65) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL28486960 0.90 ESR1 (0.65) ESR1CYP19A1CYP11B2PTGS2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017660-A2 Optical fibre, optical fibre ribbon, and optical interconnection system THE FURUKAWA ELECTRIC CO.,LTD. (JP) 2009-01-21 EP disclosed
US-7295741-B2 Optical fiber, optical fiber ribbon, and optical interconnection system THE FURUKAWA ELECTRIC CO., LTD. (JP) 2007-11-13 US disclosed
EP-1628149-A1 Optical fibre, optical fibre ribbon, and optical interconnection system The Furukawa Electric Co., Ltd. (JP) 2006-02-22 EP disclosed
US-20060034575-A1 Optical fiber, optical fiber ribbon, and optical interconnection system THE FURUKAWA ELECTRIC CO., LTD. (JP) 2006-02-16 US disclosed