Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55433 | 0.97 | ESR1 (0.74) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL4272880 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL4272869 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| Phosphine SCHEMBL28461311 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| Bromide SCHEMBL28733230 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| Hydrochloric Acid SCHEMBL28642233 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL30366689 | 0.95 | ESR1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL242155 | 0.93 | ESR1 (0.69) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL242154 | 0.93 | ESR1 (0.69) | ESR1CYP19A1CYP11B2ESR2PTGS2 | |
| SCHEMBL2121142 | 0.92 | CYP19A1 (0.71) | ESR1CYP19A1CYP11B2ESR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288184-B1 | Bis(diphenylvinyl)arene compound | SUMITOMO CHEMICAL CO (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-6875895-B2 | Such as 1,4-bis(2-(4-bromophenyl)-2-phenylethenyl)-2-(2-ethylhexyloxy)-5 -methoxybenzene; for polymerization into a light-emitting material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-05-29 | — | — | US | disclosed |
| EP-1288184-A1 | Bis(diphenylvinyl)arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | CBR1, AR, CYP1B1 | ESR1 343/4885CYP19A1 45/4885CYP11B2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.