⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428684 | 1.00 | — | — | |
| SCHEMBL31470932 | 1.00 | — | — | |
| SCHEMBL28141431 | 1.00 | SLC1A3 (0.42) | — | |
| SCHEMBL427318 | 1.00 | — | — | |
| SCHEMBL28154143 | 1.00 | SLC1A3 (0.42) | — | |
| Bromide SCHEMBL8055537 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL373444 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL373445 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2715205 | 0.97 | — | — | |
| Methane SCHEMBL27758711 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503408-B | Resolution method of (S) - (+) -2-aminobutanamide hydrochloride | 宁波赜军医药科技有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-106834372-B | Method for preparing (S) -or (R) -2-aminobutanamide by transaminase biocatalysis | 海南大学 | 2020-06-30 | — | — | CN | claimed |
| CN-111073916-A | Preparation method of D-2-aminobutanamide | 上海朴颐化学科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-109503408-A | A kind of method for splitting of (S)-(+) -2- amino-butanamide hydrochloride | 宁波赜军医药科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106834372-A | A kind of transaminase living things catalysis prepare (S) or（R）The method of 2 amino-butanamides | 海南大学 | 2017-06-13 | — | — | CN | claimed |
| US-8664228-B2 | 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid derivatives and their use as epithelial sodium channel blockers for the treatment of airway diseases | NOVARTIS AG (CH) | 2014-03-04 | — | — | US | claimed |
| EP-2285785-B1 | 3,5-DIAMINO-6-CHLORO-PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS EPITHELIAL SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF ARWAY DISEASES | NOVARTIS AG (CH) | 2012-09-05 | — | — | EP | claimed |
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | claimed |
| WO-2010111622-A2 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2010-09-30 | — | — | WO | claimed |
| CN-101130504-B | Synthesis, split and racemization method for preparing chirality medicament levetiracetam midbody (S)-(+)-2-amido butyramide hydrochlorate | ABA CHEMICALS LTD | 2010-07-28 | — | — | CN | claimed |
| CN-101735101-A | Tartrate of photoactive 2-amino amides | BEIJING KANGDACHENG MEDICAL TE | 2010-06-16 | — | — | CN | claimed |
| WO-2009138378-A1 | 3,5-DIAMINO-6-CHLORO-PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS EPITHELIAL SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF ARWAY DISEASES | NOVARTIS AG (CH) | 2009-11-19 | — | — | WO | claimed |
| CN-101130504-A | Synthesis, split and racemization of chirality medicament levetiracetam midbody (S)-(+)-2-amido butyramide hydrochlorate | ABA CHEMICALS LTD (CN) | 2008-02-27 | — | — | CN | claimed |
| CN-1015542-B | Process for the preparation of -alpha-ethyl-2-oxo-1-pyrrolidineacetamide | UCB SA (BE) | 1992-02-19 | — | — | CN | claimed |
| EP-0165919-B1 | (R)-ALPHA-ETHYL-2-OXO-1-PYRROLIDINACETAMIDE | U C B, S.A. (BE) | 1989-08-09 | — | — | EP | claimed |
| US-4837224-A | TREATING MEMORY DISORDERS | UCB SOCIETE ANONYME (BE) | 1989-06-06 | — | — | US | claimed |
| CN-85105307-A | (R)-preparation method of alpha-ethyl-2-oxo-1-pyrrolidine acetamide | — | 1987-01-14 | — | — | CN | claimed |
| EP-0165919-A1 | (R)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide | U C B, S.A. (BE) | 1985-12-27 | — | — | EP | claimed |
| US-12590059-B2 | Process for the production of levetiracetam | SUZHOU BRIGHTHOPE PHARMATECH CO., LTD (CN) | 2026-03-31 | — | — | US | disclosed |
| EP-0165919-A1 | (R)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide | U C B, S.A. (BE) | 1985-12-27 | — | — | EP | disclosed |