⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470932 | 1.00 | — | — | |
| SCHEMBL427317 | 1.00 | — | — | |
| SCHEMBL28141431 | 1.00 | SLC1A3 (0.42) | — | |
| SCHEMBL427318 | 1.00 | — | — | |
| SCHEMBL28154143 | 1.00 | SLC1A3 (0.42) | — | |
| Bromide SCHEMBL8055537 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL373444 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL373445 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2715205 | 0.97 | — | — | |
| Methane SCHEMBL27758711 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497373-B2 | Intermediate compounds used for preparing brivaracetam, preparation methods for intermediate compounds, and use | SHANGHAI BOC CHEMICAL CO., LTD. (CN) | 2025-12-16 | — | — | US | claimed |
| US-12365649-B2 | Process for the preparation of brivaracetam | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-07-22 | — | — | US | claimed |
| CN-120192939-A | Imine reductase mutant and application thereof in synthesis of brivaracetam | 中国科学院天津工业生物技术研究所 | 2025-06-24 | — | — | CN | claimed |
| CN-120193035-A | Buvaracetam and its non-pair method for biosynthesis of enantiomers | 中国科学院天津工业生物技术研究所 | 2025-06-24 | — | — | CN | claimed |
| US-20240343689-A1 | SYNTHESIS OF BRIVARACETAM | OPTIMUS DRUGS PRIVATE LIMITED (IN) | 2024-10-17 | — | — | US | claimed |
| CN-118255704-A | Synthesis method of levetiracetam | 浙江江北药业有限公司 | 2024-06-28 | — | — | CN | claimed |
| EP-4387955-A1 | SYNTHESIS OF BRIVARACETAM | OPTIMUS DRUGS PRIVATE LIMITED (IN) | 2024-06-26 | — | — | EP | claimed |
| US-20240199541-A9 | PROCESSES TO PRODUCE BRIVARACETAM | SUZHOU PENGXU PHARMATECH CO. LTD. (CN) | 2024-06-20 | — | — | US | claimed |
| CN-117700344-A | Preparation method of levetiracetam | 南京唯创远医药科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117603118-A | Preparation method of brivaracetam | 重庆天地药业有限责任公司 | 2024-02-27 | — | — | CN | claimed |
| WO-2008032027-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2008032077-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2008032036-A1 | 6-BENZIMIDAZ0LYL-2-M0RPH0LIN0-4- (AZETIDINE, PYRROLIDINE, PIPERIDINE OR AZEPINE) PYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2008032086-A1 | 2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PHENYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2006090265-A2 | PROCESSES FOR THE PREPARATION OF LEVETIRACETAM, ITS INTERMEDIATE AND THE USE OF LEVETIRACETAM IN PHARMACEUTICAL COMPOSITIONS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-31 | — | — | WO | claimed |
| CN-1015541-B | PROCESS FOR PREPARING (S)-ALPHA-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE | UCB SA (BE) | 1992-02-19 | — | — | CN | claimed |
| EP-0162036-B1 | (S)-ALPHA-ETHYL-2-OXO-1-PYRROLIDINACETAMIDE | U C B, S.A. (BE) | 1989-08-16 | — | — | EP | claimed |
| US-4837223-A | ANTIISCHEMIC AGENTS | UCB SOCIETE ANONYME (BE) | 1989-06-06 | — | — | US | claimed |
| CN-85105301-A | (S)-preparation method of alpha-ethyl-2-oxo-1-pyrrolidine acetamide | — | 1987-01-14 | — | — | CN | claimed |
| EP-0162036-A1 | (S)-alpha-ethyl-2-oxo-1-pyrrolidinacetamide | U C B, S.A. (BE) | 1985-11-21 | — | — | EP | claimed |