SCHEMBL42732

SCHEMBL42732

COC(=O)c1ccc(N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.64
CA2 P00918 4/20 0.64
CA12 O43570 3/20 0.64
CA9 Q16790 3/20 0.64
CA14 Q9ULX7 3/20 0.64
CA7 P43166 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
MAPT P10636 5/20 0.63
LMNA P02545 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP3A4 P08684 2/20 0.61
LOXL2 Q9Y4K0 1/20 0.61
MAOA P21397 1/20 0.61
TSHR P16473 2/20 0.60
GAA P10253 3/20 0.59
MAPK1 P28482 1/20 0.59
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
GLA P06280 1/20 0.57
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8359634 0.98 CA1 (0.61) CA1CA2CA12CA9CA14
SCHEMBL28108955 0.98 CA1 (0.61) CA1CA2CA12CA9CA14
Acetic Acid SCHEMBL27617108 0.94 TSHR (0.59) CA1CA2CA12CA9CA14
SCHEMBL7908252 0.94 CA1 (0.57) CA1CA2CA12CA9CA14
SCHEMBL595996 0.94 CA1 (0.62) CA1CA2CA12CA9CA14
Nitrous Acid SCHEMBL28098777 0.92 CA1 (0.55) CA1CA2CA12CA9CA14
Sulfamide SCHEMBL27783666 0.92 STS (0.62) CA1CA2CA12CA9CA14
SCHEMBL4242980 0.90 PARP10 (0.63) CA1CA2CA12CA9CA14
SCHEMBL8211759 0.90 CA1 (0.53) CA1CA2CA12CA9CA14
SCHEMBL12176925 0.88 LOXL2 (0.65) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5770 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120887867-B Quinoline biaryl heterocycle PI3K/HDAC double-target small molecule inhibitor and application thereof 浙江中医药大学 2026-05-15 CN claimed
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
US-20250257218-A1 COMPOSITIONS FOR NEAR-INFRARED LIGHT-BLOCKING FILTERS, AND IMAGE SENSORS INCLUDING NEAR-INFRARED LIGHT-BLOCKING FILTERS SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-14 US claimed
CN-119912334-A Preparation method of p-pentoxy-terphenyl methyl formate and anidulafungin side chain 广东新达瑞生物科技有限公司 2025-05-02 CN claimed
CN-119874681-A Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer 中国人民解放军北部战区总医院 2025-04-25 CN claimed
CN-119823375-A Green solid-phase synthesis method of polyarylether covalent organic framework material 南开大学 2025-04-15 CN claimed
CN-119735600-A 3-Ureido substituted thieno [2,3-b ] pyridine compound and preparation method and application thereof 华东师范大学 2025-04-01 CN claimed
CN-116102545-B Diaryl urea PI3K/mTOR/HDAC multi-target inhibitor, and pharmaceutical composition and application thereof 贵州医科大学 2025-03-25 CN claimed
CN-119613279-A N-substituted benzene ring bioisostere and preparation method thereof 上海交通大学 2025-03-14 CN claimed
CN-119613364-A MrgX2 antagonistic small molecule fluorescent probe, synthesis method thereof and application thereof in MrgX2 detection 西安交通大学 2025-03-14 CN claimed
EP-0523956-A2 Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer UNILEVER PLC (GB) 1993-01-20 EP claimed
EP-0523955-A2 Water dispersible or water soluble copolymer containing UV-absorbing monomer UNILEVER PLC (GB) 1993-01-20 EP claimed
US-5134223-A Fabric colorfastness LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-07-28 US claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed
EP-0144329-B1 PROTECTIVE COATING PROCESS FOR ALUMINUM AND ALUMINUM ALLOYS Lockheed Corporation (US) 1989-12-06 EP claimed
EP-0144329-A1 PROTECTIVE COATING PROCESS FOR ALUMINUM AND ALUMINUM ALLOYS. LOCKHEED CORP (US) 1985-06-19 EP claimed
US-4504648-A Polyurethaneurea and process for preparing the same TOYO TIRE & RUBBER COMPANY, LIMITED (JP) 1985-03-12 US claimed
WO-1984004549-A1 PROTECTIVE COATING COMPOSITION AND PROCESS FOR ALUMINUM AND ALUMINUM ALLOYS LOCKHEED CORP (US) 1984-11-22 WO claimed
US-4410670-A Process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 1983-10-18 US claimed
US-4064129-A Process for making quinacridone and its derivatives HARMON COLORS CORPORATION (US) 1977-12-20 US claimed