Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121957 | 1.00 | MAPT (0.36) | MAPTPOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL427322 | 1.00 | MAPT (0.36) | MAPTPOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL380276 | 0.90 | ELANE (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL380277 | 0.90 | ELANE (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12122067 | 0.90 | ELANE (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL379986 | 0.90 | LMNA (0.38) | MAPTPOLBLMNAUSP2SMN1; SMN2 | |
| SCHEMBL379984 | 0.90 | LMNA (0.38) | MAPTPOLBLMNAUSP2SMN1; SMN2 | |
| SCHEMBL2211066 | 0.89 | POLB (0.39) | MAPTPOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL2211062 | 0.89 | POLB (0.39) | MAPTPOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL2209340 | 0.89 | MAPT (0.39) | MAPTPOLBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058272-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-15 | — | — | US | claimed |
| US-20100048571-A1 | Organic Compounds | NOVARTIS AG | 2010-02-25 | — | — | US | claimed |
| US-20250236669-A1 | Antibodies That Bind Human Cannabinoid 1 (CB1) Receptor | BIRD ROCK BIO SUB INC (US) | 2025-07-24 | — | — | US | disclosed |
| US-20230348589-A1 | Antibodies That Bind Human Cannabinoid 1 (CB1) Receptor | BIRD ROCK BIO, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230159634-A1 | ANTIBODIES THAT BIND HUMAN CANNABINOID 1 (CB1) RECEPTOR | BIRD ROCK BIO | 2023-05-25 | — | — | US | disclosed |
| EP-3122780-B1 | ANTIBODIES THAT BIND HUMAN CANNABINOID 1 (CB1) RECEPTOR | BIRD ROCK BIO INC (US) | 2022-03-09 | — | — | EP | disclosed |
| US-10308712-B2 | Antibodies that bind human cannabinoid 1 (CB1) receptor | BIRD ROCK BIO, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180282406-A1 | ANTIBODIES THAT BIND HUMAN CANNABINOID 1 (CB1) RECEPTOR | BIRD ROCK BIO SUB, INC. | 2018-10-04 | — | — | US | disclosed |
| EP-3356833-A1 | ANTIBODIES THAT BIND HUMAN CANNABINOID 1 (CB1) RECEPTOR | BIRD ROCK BIO, INC. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-20170210797-A1 | Antibodies That Bind Human Cannabinoid 1 (CB1) Receptor | BIRD ROCK BIO SUB, INC. | 2017-07-27 | — | — | US | disclosed |
| EP-3122780-A2 | ANTIBODIES THAT BIND HUMAN CANNABINOID 1 (CB1) RECEPTOR | BIRD ROCK BIO, INC. (US) | 2017-02-01 | — | — | EP | disclosed |
| WO-2012018616-A2 | POLYPEPTIDES THAT BIND TRAIL-R1 AND TRAIL-R2 | ANAPHORE, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20120021995-A1 | Polypeptides that Bind TRAIL-R1 and TRAIL-R2 | ANAPHORE, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-8058272-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-15 | — | — | US | disclosed |
| EP-2379585-A2 | POLYPEPTIDES THAT BIND TRAIL-RI AND TRAIL-R2 | Anaphore, Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20110086806-A1 | Polypeptides that Bind IL-23R | ANAPHORE, INC. | 2011-04-14 | — | — | US | disclosed |
| WO-2011043835-A1 | POLYPEPTIDES THAT BIND IL-23R | ANAPHORE, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20100105620-A1 | Polypeptides that bind Trail-R1 and Trail-R2 | ANAPHORE, INC. | 2010-04-29 | — | — | US | disclosed |
| WO-2010042890-A2 | POLYPEPTIDES THAT BIND TRAIL-RI AND TRAIL-R2 | ANAPHORE, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20100048571-A1 | Organic Compounds | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048571-A1 | Organic Compounds | XIAP, BAX, MCL1 | MAPT 1689/4885POLB 545/4885HDAC3 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.