Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267312 | 1.00 | AR (0.54) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL4267316 | 1.00 | AR (0.54) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL11433218 | 0.92 | NR3C1 (0.54) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL11433217 | 0.92 | NR3C1 (0.54) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL11751239 | 0.90 | CYP3A4 (0.68) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL11751224 | 0.90 | CYP3A4 (0.68) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL13912204 | 0.90 | CYP3A4 (0.51) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL11573810 | 0.88 | AR (0.49) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL10629874 | 0.88 | HIF1A (0.59) | ARPGRHIF1ACYP3A4ABCB11 | |
| SCHEMBL10629866 | 0.88 | HIF1A (0.59) | ARPGRHIF1ACYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075328-A1 | PROCESS FOR THE OVEREXPRESSION OF DEHYDROGENASES | SPELLIG TILMAN | 2009-03-19 | — | — | US | disclosed |