⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297916 | 0.83 | TSHR (0.59) | — | |
| SCHEMBL4341125 | 0.81 | — | — | |
| SCHEMBL29220282 | 0.81 | TSHR (0.58) | — | |
| SCHEMBL8757277 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL6290792 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL11510451 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL20565358 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL16048299 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL9129538 | 0.77 | TSHR (0.39) | — | |
| SCHEMBL16708428 | 0.77 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496783-A | UV (ultraviolet) viscosity reducing adhesive as well as preparation method and application thereof | 南京大学 | 2024-08-16 | — | — | CN | claimed |
| EP-4329743-A1 | PYRUVATE ESTERS FOR THE TREATMENT OF VIRAL DISEASES | Birkenmeier, Gerd (DE) | 2024-03-06 | — | — | EP | claimed |
| WO-2022228651-A1 | PYRUVATE ESTERS FOR THE TREATMENT OF VIRAL DISEASES | BIRKENMEIER GERD (DE) | 2022-11-03 | — | — | WO | claimed |
| WO-2022228652-A1 | MEANS AND METHOD FOR TREATING VIRAL INFECTIONS | BIRKENMEIER GERD (DE) | 2022-11-03 | — | — | WO | claimed |
| CN-108863796-B | Method for preparing pyruvate by liquid-phase catalytic oxidation of lactate | 大连理工大学 | 2021-06-11 | — | — | CN | claimed |
| US-20160128944-A1 | COATED PARTICLES AND COMPOSITIONS COMPRISING SAME | VYOME THERAPEUTICS LIMITED (IN) | 2016-05-12 | — | — | US | claimed |
| EP-3003031-A1 | COATED PARTICLES AND COMPOSITIONS COMPRISING SAME | Vyome Biosciences Pvt Ltd (IN) | 2016-04-13 | — | — | EP | claimed |
| EP-1874407-B1 | SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS | BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG ENTWICKLUNG UND DIAGNOSTIK GMB (DE) | 2015-09-09 | — | — | EP | claimed |
| CN-104860825-A | Method for preparing pyruvate through catalytic conversion of lactic acid | DALIAN CHEMICAL PHYSICS INST | 2015-08-26 | — | — | CN | claimed |
| CN-104860824-A | Method for preparing pyruvate through catalyzing oxygen to oxidize lactate | DALIAN CHEMICAL PHYSICS INST | 2015-08-26 | — | — | CN | claimed |
| US-5595984-A | TREATMENT OF SKIN DISORDERS TO PREVENT WRINKLES, ANTIAGING AGENTS | RICHARDSON-VICKS INC. (US) | 1997-01-21 | — | — | US | claimed |
| US-5561157-A | INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS | TRISTRATA INC (US) | 1996-10-01 | — | — | US | claimed |
| US-5561158-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA, INCORPORATED | 1996-10-01 | — | — | US | claimed |
| US-5554652-A | TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554597-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554654-A | COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| EP-0273202-B1 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | SCOTT EUGENE J VAN (US) | 1995-06-21 | — | — | EP | claimed |
| EP-0599819-A2 | Additives enhancing topical actions of therapeutic agents | Van Scott, Eugene J., Dr. (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
| US-4234599-A | Treatment of skin keratoses with α-hydroxy acids and related compounds | SCOTT EUGENE J VAN | 1980-11-18 | — | — | US | claimed |