SCHEMBL4273608

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4269872	0.95	SMN1; SMN2 (0.42)	S1PR1MAPTS1PR3KDM4EHSD17B10
	SCHEMBL4275333	0.93	S1PR1 (0.38)	S1PR1MAPTS1PR3KDM4EHSD17B10
	SCHEMBL13701575	0.93	MAPT (0.37)	S1PR1MAPTKDM4EMAPK1NPC1
	SCHEMBL4270628	0.92	S1PR1 (0.43)	S1PR1MAPTS1PR3KDM4EHSD17B10
	SCHEMBL4281548	0.92	PDE4A (0.37)	S1PR1MAPTS1PR3KDM4EHSD17B10
	SCHEMBL4278848	0.92	S1PR1 (0.36)	S1PR1MAPTS1PR3KDM4EHSD17B10
	SCHEMBL13701432	0.89	MAPT (0.39)	MAPTKDM4EHSD17B10MAPK1ALDH1A1
	SCHEMBL4270647	0.89	PPARG (0.39)	S1PR1S1PR3
	SCHEMBL4278392	0.88	FPR2 (0.41)	MAPK1LMNANPSR1
	SCHEMBL4275217	0.87	PDE4B (0.39)	MAPTKDM4EMAPK1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.