SCHEMBL4274241

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4277417	0.87	CACNA1I (0.56)	CACNA1ICACNA1GCACNA1HACKR3MCHR1
	SCHEMBL4285487	0.87	CACNA1I (0.58)	CACNA1ICACNA1GCACNA1HACKR3KMT2A
	SCHEMBL20056121	0.86	CACNA1I (0.56)	CACNA1ICACNA1GCACNA1HMCHR1KMT2A
	SCHEMBL4280647	0.85	CACNA1H (0.75)	CACNA1ICACNA1GCACNA1HKCNH2
	SCHEMBL4279186	0.85	CACNA1I (0.56)	CACNA1ICACNA1GCACNA1HMCHR1KMT2A
	SCHEMBL4274727	0.85	CACNA1I (0.72)	CACNA1ICACNA1GCACNA1HACKR3ALDH1A1
	SCHEMBL4271022	0.85	CACNA1I (0.56)	CACNA1ICACNA1GCACNA1HKMT2AMEN1
	SCHEMBL4284236	0.84	CACNA1I (0.59)	CACNA1ICACNA1GCACNA1HKMT2AMEN1
	SCHEMBL4277666	0.83	CACNA1H (0.64)	CACNA1ICACNA1GCACNA1HKCNH2
	SCHEMBL4276434	0.82	CACNA1H (0.62)	CACNA1ICACNA1GCACNA1HKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.