Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271921 | 1.00 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL4275163 | 1.00 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL4280447 | 1.00 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL4279420 | 1.00 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL466284 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 | |
| SCHEMBL10705860 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 | |
| SCHEMBL16143788 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 | |
| SCHEMBL8014495 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 | |
| SCHEMBL6027841 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 | |
| SCHEMBL28554627 | 0.89 | EPHX1 (0.46) | THRBEPHX2ALDH1A1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042749-A1 | N,N-Dialkylpolyhydroxyalkylamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| EP-1676831-B1 | N,N-dialkylpolyhydroxyalkylamines | AIR PROD & CHEM (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1676831-A1 | N,N-dialkylpolyhydroxyalkylamines | Air Products and Chemicals, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20060100127-A1 | N,N-dialkylpolyhydroxyalkylamines | AIR PRODUCTS AND CHEMICALS, INC. | 2006-05-11 | — | — | US | disclosed |
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AIR PRODUCTS AND CHEMICALS, INC. | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060013780-A1 | N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines | AGL, SFN, MGAT1 | HTT 1060/4885MEN1 4517/4885THRB 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.