Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276530 | 1.00 | ADRB2 (0.40) | ADRB2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL3626476 | 0.92 | ADRB2 (0.44) | ADRB2KEAP1NFE2L2ELANE | |
| SCHEMBL3626479 | 0.92 | ADRB2 (0.44) | ADRB2KEAP1NFE2L2ELANE | |
| SCHEMBL3620916 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3620914 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4273553 | 0.83 | ADRB2 (0.51) | ADRB2 | |
| SCHEMBL4273560 | 0.83 | ADRB2 (0.51) | ADRB2 | |
| SCHEMBL3627176 | 0.80 | ADRB2 (0.50) | ADRB2 | |
| SCHEMBL3627170 | 0.80 | ADRB2 (0.50) | ADRB2 | |
| SCHEMBL274589 | 0.79 | BCHE (0.38) | ADRB2ALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547731-B2 | Formamide derivatives for the treatment of diseases | PFIZER INC (US) | 2009-06-16 | — | — | US | disclosed |